Alteration and Renovation

改建和翻新

基本信息

批准号：
8662979
负责人：
JANOS ZEMPLENI
金额：
$ 30万
依托单位：
UNIVERSITY OF NEBRASKA LINCOLN
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8662979
关键词：
Area Bioinformatics Biological Biological Assay Biometry Biostatistics Core Cell Culture Techniques Collaborations Commit Communication Computers Consult Consultations Core Facility DNA Data Data Set Diet Discipline Disease ELK1 gene Elevator Ensure Equipment Experimental Designs Floor Fostering Funding Furniture Goals Health Human Resources Individual Laboratories Laboratory Technicians Light Location MAP Kinase Gene Medical center Methodology Molecular Molecular Biology Nebraska Nutrient Obesity associated disease Phosphotransferases Postdoctoral Fellow Productivity Reagent Research Research Infrastructure Research Personnel Research Project Grants Research Training Sampling Scientist Services Signal Pathway Signal Transduction Site Solutions System Time Training Training Activity United States Universities base design endoplasmic reticulum stress exhaust experience flexibility foot graduate student improved meetings member novel nutrition obesity prevention prevent research study square foot transcription factor undergraduate student

项目摘要

The Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules (NPOD) proposes the alternation and renovation of approximately 1,961 net square feet of space on the lower level of Ruth Leverton Hall to create a state-of-the-art Molecular Biology, Bioinformatics and Biostatistics Core (MB^C). The space to be renovated will be converted into a laboratory and communications suite with an open, flexible floor plan designed to foster collaboration across scientific disciplines and provide the services needed to conduct nutrient signaling studies at the molecular level - services not currently available in Nebraska. The first component is the Nutrient Signaling Laboratory, a bench-top wet laboratory comprising 748 net square feet that includes a fume hood area, a 177-net-square-foot cell culture room, a 136-net-square-foot equipment alcove, and a 168-net-square-foot open office for the MB^C Director and technicians. This open office adjoins a 143-net-square foot Collaboration Zone for formal consultations and informal discussions among MB^C personnel and users. The second component includes a 373-net-square-foot Communications and Training Portal - a state-of-the-art communications facility for training activities for MB^C personnel. Project Leaders, the NPOD Director and other MB^C users. As a strong demonstration of institutional commitment for NPOD, the University of Nebraska-Lincoln has committed a greater than 2:1 match to support the purchase and installation of a portion of the equipment necessary to make the laboratory fully functional upon completion, and to renovate, equip, and furnish the Communications and Training Portal. Once completed, the facility will serve the needs of NPOD members and other researchers within the state and, eventually, across the nation as the MB^C's focus on nutrient signaling and molecular biology, combined with its comprehensive bioinformatics and biostatistics services, will make it unique nationally. The renovation will be completed within the first year of NPOD funding, and the MB^C will be fully operational by December 19, 2014.

内布拉斯加州通过饮食分子（NPOD）预防肥胖症中心提议在下部大约1,961平方英尺的净空间交替和翻新露丝·勒沃顿大厅的水平，以创建最先进的分子生物学，生物信息学和生物统计学核心（MB^C）。要翻新的空间将转换为实验室和通信套件采用开放，灵活的平面图，旨在促进跨科学学科的合作，并提供在分子层进行营养信号研究所需的服务 - 目前不是服务内布拉斯加州可用。第一个组件是营养信号实验室，台式湿实验室包括748净平方英尺，其中包括一个烟雾罩区域，一个177net平方英尺的牢房文化室，一个136 net平方英尺的设备壁co，以及168个net平方英尺的开放式办公室 MB^C主任和技术人员。这个开放式办公室毗邻一个143-Net平方英尺的协作区 MB^C人员和用户之间的正式咨询和非正式讨论。第二个组件包括一个373-NET平方英尺的通信和培训门户 - 最新的用于MB^C人员的培训活动的通信设施。项目负责人，NPOD主管和其他MB^C用户。作为对NPOD的机构承诺的有力证明，内布拉斯加州 - 林肯的投入大于2：1的比赛，以支持购买和安装使实验室在完成后充分发挥作用所需的部分设备，并翻新，装备和提供通信和培训门户。完成后，设施将满足NPOD成员和州内其他研究人员的需求，最终国家作为MB^C的关注营养信号传导和分子生物学，结合其全面生物信息学和生物统计学服务将在全国范围内使其独一无二。翻新将完成在NPOD资助的第一年内，MB^C将在2014年12月19日之前全面运作。