HAIR CORTISOL PREDICTS ANXIETY AND BEHAVIOR IN INFANT MONKEYS

头发皮质醇可预测幼猴的焦虑和行为

• 批准号: 8357986
• 负责人: Melinda Ann Novak
• 金额: $ 5.4万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357986
• 关键词: Anxiety; Attention; Behavior; Biological Markers; Funding; Future; Grant; Hair; Health; Human; Hydrocortisone; Infant; Macaca mulatta; Mental Health; Monkeys; National Center for Research Resources; New England; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Source; Stress; United States National Institutes of Health; base; cost; nonhuman primate

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Increased hair cortisol concentrations have been correlated with stress exposure in both human and non-human primates, and hair cortisol is now gaining attention as a biomarker for stress-related health problems. However, to date, no studies have examined its usefulness for predicting future mental health problems. This study determined whether hair cortisol was a significant predictor of later anxiety in young rhesus macaques (Macaca mulatta).

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 人类和非人类灵长类动物的毛发皮质醇浓度增加与压力暴露有关，并且毛发皮质醇现在作为与压力相关的健康问题的生物标志物而受到关注。 然而，迄今为止，还没有研究检验其在预测未来心理健康问题方面的有用性。 这项研究确定了毛发皮质醇是否是年轻恒河猴（Macaca mulatta）日后焦虑的重要预测因子。