BEHAVIORAL AND HORMONAL RESPONSES OF MONKEYS TO FG7142

猴子对 FG7142 的行为和荷尔蒙反应

• 批准号: 7958371
• 负责人: Melinda Ann Novak
• 金额: $ 6.49万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958371
• 关键词: Adult; Agonist; Anxiety; Behavioral; Benzodiazepine Receptor; Computer Retrieval of Information on Scientific Projects Database; Dose; Funding; Grant; Hormonal; Institution; Macaca mulatta; Maintenance; Monkeys; New England; Primates; Research; Research Personnel; Resources; Role; Source; Testing; United States National Institutes of Health; base; male; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have proposed a role for anxiety in the initiation and maintenance of SIB. To test this hypothesis directly, we investigated hormonal and behavioral responses of adult male rhesus macaques to various doses of the benzodiazepine (BDZ) receptor inverse agonist FG 7142.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 我们提出了焦虑在 SIB 的发生和维持中的作用。 为了直接检验这一假设，我们研究了成年雄性恒河猴对不同剂量的苯二氮卓 (BDZ) 受体反向激动剂 FG 7142 的激素和行为反应。