Dimensions of Oral Health-Related Quality of Life

口腔健康相关生活质量的维度

• 批准号: 8668770
• 负责人: Mike John
• 金额: $ 59.68万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8668770
• 关键词: Adult; Affect; Aftercare; Age; American; Area; Centers for Disease Control and Prevention (U.S.); Chemotherapy-Oncologic Procedure; Childhood; Chronic; Chronic low back pain; Clinical; Computers; Country; Data; Data Set; Decision Making; Dental; Dental General Practice; Dental Research; Dental caries; Dentistry; Dentists; Development; Dimensions; Disease; Ensure; Evaluation; Expert Opinion; Factor Analysis; General Population; Goals; Government Agencies; Health; Healthcare Systems; Individual; Information Systems; Intervention; Lead; Length; Measurable; Measurement; Measures; Methodology; Metric; Minnesota; Musculoskeletal; Oral; Oral Health Impact Profile; Oral Ulcer; Oral cavity; Oral health; Orofacial Pain; Outcome; Outcome Measure; Pain; Patient Care; Patient Outcomes Assessments; Patient Self-Report; Patients; Perception; Personal Satisfaction; Population; Practice based research; Process; Quality of Care; Quality-of-Life Assessment; Questionnaires; Recruitment Activity; Research; Research Personnel; Resources; Sampling; Structure; Surgeon; Temporomandibular Joint Disorders; Testing; Tooth structure; Validation; Work; Xerostomia; alternative treatment; base; clinical practice; comparative effectiveness; cost; design; disability; health related quality of life; improved; instrument; oral condition; oral pain; population health; response; screening; sound; theories; tool; treatment effect

DESCRIPTION (provided by applicant): In both dental research and clinical practice, how patients perceive the effects of dental interventions is essential, and one standard instrument should exist to measure and compare these effects. Here, oral health- related quality of life (OHRQoL) is the most promising concept. The most widely used OHRQoL instrument for adults, the 49-item Oral Health Impact Profile (OHIP), combines items into 7 scores that putatively measure 7 latent dimensions of perceived oral health. This set of 7 scores has been used for almost 20 years but has never been validated. In fact, recent evidence indicates that the OHIP dimensional structure is not correct, which creates a fundamental measurement problem for the assessment of OHRQoL using OHIP. The major goals of this proposal are (i) to determine which OHRQoL dimensions exist and to derive a new OHIP dimensional structure, (ii) to derive 2 new OHIP short forms and a computer adaptive testing version based on these revised dimensions, and (iii) to validate the revised OHIP dimensional structure and the newly derived versions. Existing OHIP data from 6,628 general-population subjects and 2,502 dental patients from 6 countries will be used both to derive revised OHIP dimensions by applying factor analysis and to test the newly identified dimensions. In addition, 2 new shorter OHIP forms and a computer adaptive testing version (all aimed at reducing self-reporting burden) will be developed using item response theory. Finally, a new sample of 2,000 dental patients in Minnesota will be used to validate the derived OHIP dimensions and new OHIP forms in cross-sectional and longitudinal analyses using other measures of self-reported oral health and clinical oral-health indicators. During the validation process, items from 2 other OHRQoL instruments will be integrated into the instrument to create one standard OHRQoL instrument. A unified framework for OHRQoL assessment based on OHIP will be created, and methodologies such as item response theory and bifactor analysis will ensure that scores from newly derived short-form OHIP versions are compatible with scores from longer OHIPs (score equating). The relationship of OHIP scores to health-related quality of life outcome measures will be explored using methodology from NIH's Patient-Reported Outcomes Measurement Information System (PROMIS). The revised OHIP will measure perceived oral health with a valid set of OHIP dimension scores from instruments with different lengths that will nevertheless be compatible across settings. A profile of sound OHIP dimension scores can become dentistry's standard tool for assessing oral health and treatment effects from the patient's perspective. The revised OHIP will allow effects from all oral interventions to become comparable, aiding dentists and patients in their evaluation of treatment alternatives and informing health care systems for setting resource priorities.

描述（由申请人提供）：在牙科研究和临床实践中，患者如何看待牙齿干预的影响至关重要，并且应该存在一种标准工​​具来衡量和比较这些效果。在这里，与口腔健康相关的生活质量（OHRQOL）是最有前途的概念。 49项口腔健康影响概况（OHIP）是成人最广泛使用的OHRQOL仪器，将项目结合在7个分数中，这些分数旨在测量7个可感知口腔健康的潜在维度。这套7分已经使用了将近20年，但从未得到过验证。实际上，最近的证据表明，OHIP尺寸结构不正确，这为使用OHIP评估OHRQOL的基本测量问题提供了基本的测量问题。该提案的主要目标是（i）确定存在哪个OHRQOL维度并得出新的OHIP维度结构，（ii）根据这些修订后的维度得出2种新的OHIP短表和一个计算机自适应测试版本，（III），以验证修订后的OHIP尺寸结构和新衍生的版本。现有的OHIP数据来自6,628名综合受试者和来自6个国家的2,502名牙科患者的现有数据，既可以通过应用因子分析并测试新确定的维度来得出修订的OHIP维度。此外，将使用项目响应理论开发2种新的较短的OHIP表格和一个计算机自适应测试版本（旨在减轻自我报告负担）。最后，使用其他自我报告的口腔健康和临床口腔健康指标的措施，将使用2,000名明尼苏达州的2,000名牙科患者的新样本来验证横断面和纵向分析中的衍生OHIP维度和新的OHIP形式。在验证过程中，将将来自其他两种Ohrqol仪器的项目集成到该仪器中，以创建一种标准的Ohrqol仪器。将创建一个基于OHIP的OHRQOL评估的统一框架，并且诸如项目响应理论和双因素分析之类的方法将确保新得出的短形式OHIP版本的得分与更长的OHIP（分数等同）的得分兼容。将使用NIH患者报告的结果测量信息系统（Promis）中的方法来探索OHIP评分与与健康相关的生活质量结果指标的关系。修订后的OHIP将通过一组有效的OHIP维度得分来衡量口腔健康，这些仪器的长度不同，但在各个环境中仍然兼容。从患者的角度来看，声音OHIP维度得分的概况可以成为牙科评估口腔健康和治疗效果的标准工具。修订后的OHIP将允许所有口服干预措施的影响，可帮助牙医和患者评估治疗替代方法，并告知医疗保健系统以确定资源优先级。