Dimensions of Oral Health-Related Quality of Life

口腔健康相关生活质量的维度

• 批准号: 8469469
• 负责人: Mike John
• 金额: $ 50.61万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8469469
• 关键词: Adult; Affect; Aftercare; Age; American; Area; Centers for Disease Control and Prevention (U.S.); Chemotherapy-Oncologic Procedure; Childhood; Chronic; Chronic low back pain; Clinical; Computers; Country; Data; Data Set; Decision Making; Dental; Dental General Practice; Dental Research; Dental caries; Dentistry; Dentists; Development; Dimensions; Disease; Ensure; Evaluation; Expert Opinion; Factor Analysis; General Population; Goals; Government Agencies; Health; Healthcare Systems; Individual; Information Systems; Intervention; Lead; Length; Measurable; Measurement; Measures; Methodology; Metric; Minnesota; Musculoskeletal; Oral; Oral Health Impact Profile; Oral Ulcer; Oral cavity; Oral health; Orofacial Pain; Outcome; Outcome Measure; Pain; Patient Care; Patient Outcomes Assessments; Patient Self-Report; Patients; Perception; Personal Satisfaction; Population; Practice based research; Process; Quality of Care; Quality-of-Life Assessment; Questionnaires; Recruitment Activity; Research; Research Personnel; Resources; Sampling; Structure; Surgeon; Temporomandibular Joint Disorders; Testing; Tooth structure; Validation; Work; Xerostomia; alternative treatment; base; clinical practice; comparative effectiveness; cost; design; disability; health related quality of life; improved; instrument; oral condition; oral pain; population health; response; screening; sound; theories; tool; treatment effect

DESCRIPTION (provided by applicant): In both dental research and clinical practice, how patients perceive the effects of dental interventions is essential, and one standard instrument should exist to measure and compare these effects. Here, oral health- related quality of life (OHRQoL) is the most promising concept. The most widely used OHRQoL instrument for adults, the 49-item Oral Health Impact Profile (OHIP), combines items into 7 scores that putatively measure 7 latent dimensions of perceived oral health. This set of 7 scores has been used for almost 20 years but has never been validated. In fact, recent evidence indicates that the OHIP dimensional structure is not correct, which creates a fundamental measurement problem for the assessment of OHRQoL using OHIP. The major goals of this proposal are (i) to determine which OHRQoL dimensions exist and to derive a new OHIP dimensional structure, (ii) to derive 2 new OHIP short forms and a computer adaptive testing version based on these revised dimensions, and (iii) to validate the revised OHIP dimensional structure and the newly derived versions. Existing OHIP data from 6,628 general-population subjects and 2,502 dental patients from 6 countries will be used both to derive revised OHIP dimensions by applying factor analysis and to test the newly identified dimensions. In addition, 2 new shorter OHIP forms and a computer adaptive testing version (all aimed at reducing self-reporting burden) will be developed using item response theory. Finally, a new sample of 2,000 dental patients in Minnesota will be used to validate the derived OHIP dimensions and new OHIP forms in cross-sectional and longitudinal analyses using other measures of self-reported oral health and clinical oral-health indicators. During the validation process, items from 2 other OHRQoL instruments will be integrated into the instrument to create one standard OHRQoL instrument. A unified framework for OHRQoL assessment based on OHIP will be created, and methodologies such as item response theory and bifactor analysis will ensure that scores from newly derived short-form OHIP versions are compatible with scores from longer OHIPs (score equating). The relationship of OHIP scores to health-related quality of life outcome measures will be explored using methodology from NIH's Patient-Reported Outcomes Measurement Information System (PROMIS). The revised OHIP will measure perceived oral health with a valid set of OHIP dimension scores from instruments with different lengths that will nevertheless be compatible across settings. A profile of sound OHIP dimension scores can become dentistry's standard tool for assessing oral health and treatment effects from the patient's perspective. The revised OHIP will allow effects from all oral interventions to become comparable, aiding dentists and patients in their evaluation of treatment alternatives and informing health care systems for setting resource priorities.

描述（由申请人提供）：在牙科研究和临床实践中，患者如何看待牙科干预的效果至关重要，并且应该存在一种标准工​​具来测量和比较这些效果。在这里，口腔健康相关的生活质量（OHRQoL）是最有前途的概念。包含 49 项的口腔健康影响概况 (OHIP) 是成人使用最广泛的 OHRQoL 工具，将项目合并为 7 个分数，假定衡量感知口腔健康的 7 个潜在维度。这组 7 个分数已经使用了近 20 年，但从未得到验证。事实上，最近的证据表明 OHIP 维度结构不正确，这为使用 OHIP 评估 OHRQoL 带来了基本的测量问题。该提案的主要目标是 (i) 确定存在哪些 OHRQoL 维度并导出新的 OHIP 维度结构，(ii) 导出 2 个新的 OHIP 简表和基于这些修订维度的计算机自适应测试版本，以及 (iii) ）以验证修订后的 OHIP 维度结构和新派生的版本。来自 6 个国家的 6,628 名普通人群和 2,502 名牙科患者的现有 OHIP 数据将用于通过应用因子分析得出修订后的 OHIP 维度，并测试新确定的维度。此外，还将利用项目反应理论开发 2 个新的较短的 OHIP 表格和一个计算机自适应测试版本（全部旨在减少自我报告负担）。最后，明尼苏达州 2,000 名牙科患者的新样本将用于使用自我报告的口腔健康和临床口腔健康指标的其他测量方法，在横断面和纵向分析中验证派生的 OHIP 维度和新的 OHIP 形式。在验证过程中，其他 2 个 OHRQoL 工具中的项目将集成到该工具中，以创建一个标准 OHRQoL 工具。将创建基于 OHIP 的统一 OHRQoL 评估框架，项目反应理论和双因素分析等方法将确保新派生的简短 OHIP 版本的分数与较长 OHIP 的分数兼容（分数相等）。将使用 NIH 患者报告结果测量信息系统 (PROMIS) 的方法来探讨 OHIP 评分与健康相关生活质量结果测量的关系。修订后的 OHIP 将使用不同长度仪器的一组有效 OHIP 维度分数来测量感知的口腔健康，但这些仪器在不同环境下都兼容。健全的 OHIP 维度评分概况可以成为牙科从患者角度评估口腔健康和治疗效果的标准工具。修订后的 OHIP 将使所有口腔干预措施的效果具有可比性，帮助牙医和患者评估治疗方案，并告知医疗保健系统确定资源优先级。