Development of a PROMIS measure for adult dental patients

为成年牙科患者开发 PROMIS 措施

基本信息

批准号：
10458620
负责人：
Mike John
金额：
$ 55.01万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10458620
关键词：
Adult Affect Appearance Area Clinical Complex Complex Analysis Data Data Analyses Data Collection Dental Dental General Practice Dental caries Dentistry Development Dimensions Disease Evaluation Focus Groups Four-dimensional Goals Government Agencies Group Interviews Health Health Professional Healthcare Systems Impairment Individual Individual Differences Information Systems International Intervention Intuition Jaw Length Letters Mastication Measurable Measurement Measures Methodology Methods Mouth Diseases Nature Numerical value Oral Oral Characters Oral health Orofacial Pain Outcome Measure Pain Patient Outcomes Assessments Patient Representative Patient Self-Report Patients Process Property Psychometrics Questionnaires Reporting Research Research Personnel Resources Sampling Severities Solid Source Standardization Time Tooth structure Work advanced system base care seeking cognitive interview dentofacial design experience flexibility health assessment health data health related quality of life improved instrument malignant mouth neoplasm oral condition orofacial patient population prevent psychosocial response systematic review theories tool trait treatment effect

项目摘要

Fourteen years ago, PROMIS, the Patient Reported Outcome Measurement Information System, was created as the most advanced system of patient-reported outcome (PRO) measures. It promises efficient, reliable, and valid assessments of how patients perceive their health; however, no measures specific to oral health are available. This situation impedes solid PRO measurement in dentistry and also prevents PROMIS from capturing health more comprehensively. We propose to develop for adults a set of four oral health instruments using PROMIS methodology, based on the recently determined dimensions of oral health-related quality of life, OHRQoL (Oral Function, Orofacial Pain, Orofacial Appearance, Psychosocial Impact). These dimensions represent the main areas where patients perceive the impact of oral disorders. More than 53 patient-reported oral health instruments for adult patients would merge into a standardized, flexible and precise metric to measure oral health impact across oral conditions and dental settings. A profile of four scores, based on the four dimensions, would form the patient-reported oral health metric and characterize a patient’s standing in the space of patient-reported oral health with four “coordinates” – one for each dimension. The goals of this proposal are (i) to explore how well available instruments cover the spectrum of the four patient-reported oral health dimensions Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact, (ii) to develop four preliminary item banks, one for each dimension, (iii) to develop four final item banks, one for each dimension, and (iv) to develop four fixed-length instruments based on the item banks, one for each dimension. Existing OHRQoL and other patient-reported oral health data from 2,115 dental patients will be used in secondary data analyses to explore the severity spectrum of the four patient-reported oral health dimensions and how well available questionnaire items cover this spectrum. Questionnaire items from 53 already identified self-report instruments will be supplemented by a systematic search for new questionnaires/items. All identified items will undergo a mixed-methods approach to be synthesized through focus groups and cognitive interviews with representative patient groups. Our process will follow the PROMIS Qualitative Item Review method to identify, evaluate, and revise items to create four preliminary item banks. Next, in a new sample of 2,000 dental patients covering the entire spectrum of functional, painful, aesthetical, and broader psychosocial problems related to oral disorders, the previously generated four preliminary item banks will be investigated and calibrated using item response theory analyses to derive four final item banks. A fixed-length instrument will be derived from each item bank, and its psychometric properties will be evaluated. This project will introduce PROMIS methodology to an important patient population, adult dental patients. Four scores characterizing Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact would become the standard tool for assessing oral conditions and treatment effects from the adult patient’s perspective.

十四年前，创建了 PROMIS（患者报告结果测量信息系统）作为最先进的患者报告结果 (PRO) 测量系统，它承诺高效、可靠和可靠。对患者如何看待自己的健康进行有效的评估；然而，没有针对口腔健康的具体措施这种情况阻碍了牙科领域的可靠 PRO 测量，也阻碍了 PROMIS 的捕获。我们建议为成人开发一套四件套的口腔健康工具。 PROMIS 方法基于最近确定的口腔健康相关生活质量维度， OHRQoL（口腔功能、口面部疼痛、口面部外观、社会心理影响）。超过53名患者报告成人患者的口腔健康仪器将合并成标准化、灵活且精确的指标来测量口腔健康对口腔状况和牙科环境的影响基于四个分数。尺寸，将形成患者报告的口腔健康指标并表征患者在空间中的站立情况患者报告的口腔健康状况有四个“坐标”——每个维度一个。该提案的目标是。 (i) 探讨现有工具如何覆盖患者报告的四种口腔健康状况维度口腔功能、口面部疼痛、口面部外观和社会心理影响，(ii) 制定四个维度初步项目库，每个维度一个， (iii) 开发四个最终项目库，每个维度一个， (iv) 基于项目库开发四种固定长度工具，每个维度一个。来自 2,115 名牙科患者的现有 OHRQoL 和其他患者报告的口腔健康数据将用于二级评估数据分析，探讨患者报告的四个口腔健康维度的严重程度以及效果如何可用的调查问卷项目涵盖了这一范围，调查问卷项目来自 53 个已确定的自我报告。将通过对新调查问卷/项目的系统搜索来补充工具。通过焦点小组和认知访谈进行综合的混合方法我们的流程将遵循 PROMIS 定性项目审查方法来识别、接下来，在 2,000 名牙科患者的新样本中评估和修改项目以创建四个初步项目库。涵盖与相关的功能性、疼痛性、美观性和更广泛的心理社会问题的整个范围口腔疾病，将使用先前生成的四个初步项目库进行调查和校准项目反应理论分析得出四个最终项目库，每个项目库都会派生出一个固定长度的工具。项目库及其心理测量特性将被评估。该项目将向重要的患者群体——成年牙科患者介绍 PROMIS 方法。表征口腔功能、口面部疼痛、口面部外观和心理社会影响的分数成为从成年患者的角度评估口腔状况和治疗效果的标准工具。