Molecular Medicine Training Program

分子医学培训计划

• 批准号: 8685276
• 负责人: PAUL E DICORLETO
• 金额: $ 18.05万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8685276
• 关键词: Molecular Medicine; Training Programs

DESCRIPTION (provided by applicant): The Molecular Medicine Training Program of the Case Western Reserve University School of Medicine is specifically designed to train pre-doctoral students to take scientific advances from "bench to bedside". It takes advantage of four factors to create an environment particularly suited to this purpose. First, this Program is located in the Lerner Research Institute where physicians and scientists from both the Cleveland Clinic and the School of Medicine have historically worked closely together to focus cutting edge research upon the causes and treatments of human illness. Second, a novel core curriculum has been designed throughout the first year to provide a solid foundation in basic scientific principles presented in the context of human organ systems and disease. Research presentations and rotations, seminars journal clubs, and a student retreat reinforce the translational application of the basic scientific principles throughout training. Third, the Training Program contains a broad range of trainers heading outstanding translational research laboratories in which our trainees perform rotations and thesis work. The range and strength of these laboratories, their collaborative interactions, and the commitment of the trainers to support of the Training Program is evidence of the collegial scientific environment within the Training Program. Finally, to ensure that each of the trainees comes to understand the clinical aspects of their area of investigation, each selects a Clinical Mentor who helps organize an individual clinical experience. Through this experience trainees are introduced to patient diagnosis and treatment on a first hand basis. To further emphasize the connection to clinical practice, students in the Training Program take a joint course with medical students of the Lerner College of Medicine. Experience has shown that these medical students who are in training to be physician scientists, and our trainees who are finding clinical application to basic scientific observations, have much to learn from one another. This proposal seeks funding for 7 trainees within the Training Program. With admission of its fourth class, it has become clear that the Training Program has gained national recognition and attracted an ever increasing number of applicants, with 27 training grant eligible trainees currently associated with the Program. The trainees are eagerly preparing to take their places as the leaders of the next generations of NIH funded laboratories translating basic scientific principles to address patient needs. The fact that this Program was specifically designed to address the needs for translational research identified in the recent NIH roadmap explains its youth, and emphasizes the importance of promoting its growth and maturation.

描述（由申请人提供）：西方储备大学医学院的分子医学培训计划专门旨在培训博士前的学生，以从“长凳到床边”进行科学进步。它利用四个因素创造一个特别适合此目的的环境。首先，该计划位于Lerner研究所，来自克利夫兰诊所和医学院的医生和科学家历来紧密合作，将尖端研究集中在人类疾病的原因和治疗上。其次，在整个第一年设计了一种新颖的核心课程，以在人体器官系统和疾病的背景下为基本科学原理提供坚实的基础。研究演示和轮换，研讨会俱乐部以及学生静修会加强了整个培训中基本科学原理的翻译应用。第三，培训计划包含广泛的培训师，领导着出色的翻译研究实验室，我们的学员在其中进行轮换和论文工作。这些实验室的范围和力量，他们的协作互动以及培训师支持培训计划的承诺是培训计划中大学科学环境的证据。最后，为了确保每个学员都了解其调查领域的临床方面，每个人都选择了一个临床导师，以帮助组织单个临床经验。通过这一经验，请介绍受训者对患者的诊断和治疗。为了进一步强调与临床实践的联系，培训计划中的学生与勒纳医学院的医学生一起参加了联合课程。经验表明，这些正在接受培训的医学生成为医师科学家，而我们正在临床应用临床科学观察的学员有很多彼此学习的知识。该建议在培训计划中寻求7位学员的资金。随着其四等级别的承认，很明显，该培训计划已获得了国家认可并吸引了越来越多的申请人，目前与该计划相关的27名培训授予的合格学员。学员们热切准备将自己的位置作为下一代NIH资助的实验室的领导人，这些实验室翻译了基本的科学原则以满足患者的需求。该计划的专门设计旨在满足最近NIH路线图中确定的转化研究需求的事实，解释了其青年，并强调促进其成长和成熟的重要性。