Fogarty HIV Research Training Program for Low and Middle-Income Countries

福格蒂低收入和中等收入国家艾滋病毒研究培训计划

• 批准号: 8516232
• 负责人: MYRON E ESSEX
• 金额: $ 27.24万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2018-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8516232
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Adult; Advisory Committees; Africa; Anti-Retroviral Agents; Area; Botswana; Clinical; Country; Developing Countries; Doctor of Philosophy; Educational workshop; Faculty; Funding; Goals; Government; HIV; Health; High Prevalence; Incidence; Income; Individual; Institutes; Journals; Mentors; Monitor; Patients; Performance; Pharmaceutical Preparations; Physicians; Positioning Attribute; Postdoctoral Fellow; Prevention Research; Preventive Intervention; Publications; Relative (related person); Research; Research Activity; Research Project Grants; Research Training; Site; Training; Training Programs; base; experience; pre-doctoral; programs; success

PROJECT ABSTRACT The focus for this proposal is on prevention research in Botswana to reduce incidence of HIV/AIDS. This is central to the current research activities of the faculty mentors, who collaborate extensively with each other and with key partners at the Botswana site. Our partner for training is the Botswana Harvard AIDS Institute Partnership (BHP), a limited liability nonprofit corporation (LLC) with the Ministry of Health (MOH) in Botswana. The BHP is the largest HIV/AIDS research organization in Botswana, and one of the largest in Africa. The long- term goals and objectives of this training program are to train research leaders who can take responsibility for the BHP within the next 5-10 years, and to staff the MOH with local AIDS experts. Botswana currently has the second-highest prevalence of HIV in the world for adults (25%), but has also had the highest rate of antiretroviral drug treatment (ART) for patients with AIDS (about 90%, according to WHO). The government of Botswana, the training faculty at Harvard, and the key collaborators at BHP have now decided to focus their efforts on prevention research. A new research grant based on a combination of prevention interventions includes participation by 10 of the 14 Harvard training faculty. AIDS-related courses, seminars, and workshops are available for trainees. We have requested funds for 2 predoctoral and 3 postdoctoral positions each year. We estimate that we will train about 18 trainees over 5 years, allowing for multiple years for each PhD candidate and some postdoctoral fellows, and assuming several short-term trainees could fill a single annual training slot. Stipends will be based on current degrees and research experience; thus an MD on an MS or PhD program would be eligible for a postdoctoral-level stipend. All trainees would have at least a BSc degree. We estimate that about half will be physicians with clinical experience. Some will be postdoctoral fellows who have PhD's in a related area but no experience in AIDS research. Each trainee will have a principal advisor and a faculty advisory committee. Selection of trainees is based on previous academic performance, references, experience, and assurance that the candidates will return to participate in AIDS research in Botswana. The quality of the program will be monitored by a Training Advisory Committee composed of experts from the US and from developing countries. The success of the training program will be judged by the relative increase in senior research positions at BHP and MOH that are individuals who were trained by this program after the second and fourth years. Success will also be judged by the implementation of successful prevention research programs that involve trainees, numbers of trainee publications in high-impact journals, and number of staff positions filled by former trainees at the BHP and the Ministry of Health.

项目摘要 该提案的重点是博茨瓦纳的预防研究，以减少艾滋病毒/艾滋病的发病率。这是 教师导师当前研究活动的核心，他们彼此广泛合作， 与博茨瓦纳工厂的主要合作伙伴。我们的培训合作伙伴是博茨瓦纳哈佛艾滋病研究所 合作伙伴关系 (BHP) 是一家与博茨瓦纳卫生部 (MOH) 合作的有限责任非营利公司 (LLC)。 必和必拓是博茨瓦纳最大的艾滋病毒/艾滋病研究组织，也是非洲最大的艾滋病毒/艾滋病研究组织之一。长- 该培训计划的学期目标和目标是培训能够承担以下责任的研究领导者 必和必拓将在未来 5-10 年内向 BHP 提供支持，并为卫生部配备当地艾滋病专家。博茨瓦纳目前拥有 成人艾滋病毒感染率位居世界第二（25%），但感染率也最高 艾滋病患者接受抗逆转录病毒药物治疗（ART）（根据世界卫生组织的数据，大约 90%）。政府 博茨瓦纳、哈佛大学的培训师以及必和必拓的主要合作者现在决定集中精力 努力做好预防研究。基于预防干预措施组合的新研究资助 包括 14 名哈佛大学培训教师中的 10 名参与。 为学员提供与艾滋病相关的课程、研讨会和讲习班。我们已请求资金 2 每年招收博士前和博士后3名。我们预计将培训 5 岁以上学员约 18 名 年，允许每个博士候选人和一些博士后研究员有多年的时间，并假设 几个短期受训人员可以填补一个年度培训名额。津贴将基于当前学位 和研究经验；因此，硕士或博士课程的医学博士将有资格获得博士后级别 助学金。所有学员都至少拥有理学学士学位。我们估计大约一半将是医生 临床经验。有些人将是博士后研究员，他们拥有相关领域的博士学位，但没有相关领域的经验。 艾滋病研究。每个实习生都会有一名首席顾问和一个教职顾问委员会。选择 受训者基于以前的学业表现、推荐信、经验和保证 候选人将返回博茨瓦纳参加艾滋病研究。计划的质量将受到监控 由来自美国和发展中国家的专家组成的培训咨询委员会负责。这 培训计划的成功将通过必和必拓高级研究职位的相对增加来判断 卫生部是在第二年和第四年之后接受该计划培训的人员。成功也会 判断标准是预防研究计划是否成功实施，其中涉及受训者、人数 受训者在高影响力期刊上发表的出版物，以及必和必拓前受训者担任的员工职位数量 和卫生部。