Early Childhood Predictors of Adolescent Substance Use in a High Risk Sample

高风险样本中青少年药物使用的早期儿童预测因素

• 批准号: 8510285
• 负责人: Rina D Eiden
• 金额: $ 18.88万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-05 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8510285
• 关键词: Adolescence; Adolescent; Age; Alcohol abuse; Alcohol consumption; Alcohol or Other Drugs use; Alcoholic Intoxication; Behavior assessment; Birth Records; Child; Cigarette; Cognition; Complex; Control Groups; Data; Development; Developmental Process; Drug usage; Early Intervention; Expectancy; Family; Fathers; Goals; Individual; Informal Social Control; Intervention; Knowledge; Link; Literature; Marijuana Smoking; Mediating; Mediation; Mental Health; Methods; Modeling; New York; Nursery Schools; Outcome; Parenting behavior; Parents; Pathway interactions; Population; Prevention program; Prevention strategy; Preventive Intervention; Problem behavior; Process; Psychopathology; Recruitment Activity; Reporting; Research; Risk; Risk Behaviors; Risk Factors; Role; Sampling; School-Age Population; Schools; Security; Staging; Testing; Time; adolescent substance use; base; behavior observation; boys; children of alcoholics; clinically significant; contextual factors; design; drinking; early childhood; early onset; eighth grade; follow-up; fourth grade; girls; high risk; high school; infancy; intervention program; kindergarten; model development; neuropsychological; parental alcoholism; parental monitoring; parental role; peer; prevent; problem drinker; programs; prospective; psychologic; public health relevance; reduced substance abuse; reduced substance use; sixth grade; teacher; twelfth grade; underage drinking; underage drinking prevention

DESCRIPTION (provided by applicant): Children of alcoholics (COAs) are a large and critical component of the underage drinking population. They have a 4 to 10 time's greater risk of developing clinically significant alcohol problems, an earlier onset of drinking, and a more rapid progression from alcohol use to abuse. The major goal of this application is to obtain critical data regarding key risk and protective factors from early childhood to predict adolescent substance use and other risky behaviors in a high risk sample characterized by parents' alcohol problems and a demographically matched control group. There is ample evidence from the general psychological literature that early intervention is most effective in preventing trajectoris of risk, especially in high risk populations. Thus, knowledge about predictors of substance use beginning in infancy is crucial for determining the content of early intervention targeted at processes that may impact substance use risk among COAs. Targeting developmental processes that are of etiological significance for substance use and focusing on reducing or bolstering key risk and protective mechanisms may be highly effective as a prevention strategy for reducing substance abuse risk among COAs. This is the only sample of COAs with multi-method (observational, neuropsychological, parent, child, and teacher report) assessments of key risk and protective mechanisms (attachment, parenting quality, self-regulation, behavior problems) beginning in infancy. It is expected that the results from the current application will inform the timing and content of a prevention program focused on precursors of underage drinking and drug use among COAs. The sample will consist of 227 (102 controls, 125 COAs) families who were recruited in infancy (111 girls and 116 boys). Multi-method assessments of stage salient developmental outcomes as well as potential risk and protective mechanisms were conducted at 12, 18, 24, and 36 months of child age, with follow-up assessments in kindergarten, 4th, 6th, and 8th grades. These children will be entering high school and in the current application we propose to assess substance use and other risky behaviors as well as proximal predictors of risk such as parental monitoring, peer use, delinquency, and substance use cognitions (expectancies, motives, norms). Key aims tested will be as follows: to examine the role of trajectories of behavior problems from 18 months to high school as predictors of adolescent substance use; to examine the role of self-regulation as mediating or moderating the association between parents' alcohol problems and trajectories of substance use from early to late adolescence; and to examine the role of parental warmth/sensitivity and/or attachment security in infancy. The results will be used to develop an early intervention program for children of alcoholics designed to reduce substance use risk among these high risk children. Data from the current application will be critical to inform the timing and content of this early interventio program.

描述（由申请人提供）：酗酒者（COAS）是未成年人饮酒人群的大型组成部分。他们有4至10次出现临床意义的酒精问题，早期饮酒的风险以及从酒精使用到滥用的迅速发展。本应用的主要目的是获取有关幼儿期的关键风险和保护因素的关键数据，以预测以父母的酒精问题和人口统计学匹配的对照组为特征的高风险样本中的青少年使用和其他风险行为。从一般心理文献中有足够的证据表明，早期干预最有效地防止风险轨迹，尤其是在高风险人群中。因此，关于从婴儿期开始使用的物质使用预测因素的知识对于确定可能影响COA中药物使用风险的过程的早期干预措施的内容至关重要。针对使用物质使用以及专注于降低或加强关键风险和保护机制具有病因意义的发展过程可能是一种非常有效的预防策略，作为减少COAS中药物滥用风险的一种预防策略。这是对关键风险和保护机制（依恋，育儿质量，自我调节，行为问题）的多方法（观察，神经心理学，父母，孩子和教师报告）的唯一COAS样本。预计当前申请的结果将为预防计划的时间和内容提供信息，该计划侧重于COAS中未成年人饮酒和吸毒的先驱。该样本将包括在婴儿期招募的227个（102个对照，125个COA）家庭（111名女孩和116个男孩）。阶段显着发展结果以及潜在风险和保护机制的多方法评估在儿童年龄的12、18、24和36个月进行，并在幼儿园，第4、6、6和8年级进行了随访评估。这些孩子将进入高中，在当前的应用中，我们建议评估物质使用和其他风险行为以及近端的风险预测因素，例如父母监测，同伴使用，犯罪和毒品使用认知（预期，动机，规范）。测试的主要目标将如下：研究从18个月到高中的行为问题的作用，作为青少年使用物质的预测因素；探讨自我调节作为介导或调节父母的酒精问题与从青春期早期使用物质使用轨迹之间的关联的作用；并检查父母的温暖/敏感性和/或依恋安全性在婴儿期的作用。结果将用于制定针对儿童的早期干预计划 旨在减少这些高风险儿童中药物使用风险的酒精中毒。当前应用程序中的数据将至关重要，以告知此早期干预程序的时间和内容。