CLINICAL DIAGNOSIS/BEHAVIORAL ASSESSMENT CORE

临床诊断/行为评估核心

• 批准号: 8076867
• 负责人: Harold Hill Goldsmith
• 金额: $ 14.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8076867
• 关键词: Address; Adolescence; Adolescent; Affect; Age; Anxiety; Anxiety Disorders; Behavior; Behavior assessment; Behavioral; Child; Code; DSM-IV; Data; Development; Diagnosis; Diagnostic; Ensure; Health behavior; Interview; Laboratories; Licensing; Literature; Longitudinal Studies; Measures; Mood Disorders; Paper; Participant; Problem behavior; Protocols documentation; Psychometrics; Psychopathology; Publishing; Questionnaires; Receiver Operating Characteristics; Risk Factors; Sampling; Scheme; Screening procedure; Structure; Symptoms; Trier Social Stress Test; Videotape; Visit; clinical Diagnosis; human subject; innovation; instrument

The Clinical Diagnosis/Behavioral Assessment Core (Core C) will be responsible for ensuring that a common set of age appropriate, interview, behavioral, and diagnostic measures are used in all projects that employ human subjects. The aims of Projects 2 and 3 are highly complementary; thus, they employ similar protocols for the laboratory visits done in the late adolescent age period. As a central activity, the core will conduct structured diagnostic interviews by licensed clinicians on select groups of participants, thus following up on diagnoses made earlier in these longitudinal studies and benefiting Projects 2, 3, 4, and 5. These K-SADS interviews will allow results to be assimilated to the literature on anxiety disorders as defined by DSM-IV. The presence or absence of clinical diagnoses will prominently figure into addressing scientific aims on Projects 2, 3, 4, and 5. Core C will pay for diagnostic interviews and manage the resulting data. Projects 2 and 3 will screen their entire samples for behavioral problems in late adolescence, with the MacArthur Health and Behavior Questionnaire (HBQ) as the main screening instrument. The projects will conduct this screening, but Core C will manage the resulting data in a uniform manner and facilitate analyses across projects. The Trier Social Stress Test (TSST) figures prominently in both Project 2 and 3, and relates conceptually to all projects. Core 2 will facilitate uniform administration of the TSST and conduct behavioral coding of videotapes taken during the TSST. The development and implementation of a coding scheme for affect and behavior during the TSST will be an innovative contribution of Core C. Finally, with our consultant Dr. Kraemer on Project 2, the Core will publish methodological papers on two topics: (1) Clarifying the relationship between categorical field diagnoses of child psychopathology and prior and concurrent dimensional symptom scores from the HBQ and other measures using Receiver Operating Characteristic (ROC) curve approaches. Many developmental factors will be incorporated into these analyses. (2) Examining the psychometric quality of instruments used in the assessment protocols. These latter measures capture key risk factors for adolescent anxiety.

临床诊断/行为评估核心（核心 C）将负责确保共同的 所有项目均采用一套适合年龄的访谈、行为和诊断措施 人类受试者。项目2和3的目标高度互补；因此，他们采用类似的协议 用于在青春期后期进行的实验室检查。 作为一项核心活动，核心将由有执照的临床医生对选定的对象进行结构化诊断访谈 参与者小组，从而跟进这些纵向研究中早期做出的诊断，并且 使项目 2、3、4 和 5 受益。这些 K-SADS 访谈将使结果同化到 有关 DSM-IV 定义的焦虑症的文献。临床诊断的存在或不存在将 突出地涉及解决项目 2、3、4 和 5 的科学目标。核心 C 将支付诊断费用 访谈并管理结果数据。 项目 2 和 3 将筛查整个样本是否存在青春期后期的行为问题， 麦克阿瑟健康与行为问卷（HBQ）作为主要筛查工具。这些项目将 进行此筛选，但 Core C 将以统一的方式管理结果数据并促进分析 跨项目。 特里尔社会压力测试 (TSST) 在项目 2 和 3 中都很突出，并且在概念上相关 到所有项目。核心2将促进TSST的统一管理并进行行为编码 TSST 期间拍摄的录像带。情感和情感编码方案的开发和实施 TSST 期间的行为将是 Core C 的创新贡献。 最后，与我们项目 2 的顾问 Kraemer 博士一起，核心将发表关于两个项目的方法论论文 主题：（1）阐明儿童精神病理学的分类现场诊断与既往诊断之间的关系 HBQ 的并发维度症状评分以及使用接收器操作的其他测量 特征 (ROC) 曲线方法。许多发展因素将被纳入其中 分析。 (2) 检查评估方案中使用的仪器的心理测量质量。这些 后者的措施捕捉了青少年焦虑的关键危险因素。