Cardiac Remodeling, Signaling, Matrix and Heart Function

心脏重塑、信号传导、基质和心脏功能

基本信息

批准号：
8527455
负责人：
DAVID L. WOODLAND
金额：
$ 1.38万
依托单位：
KEYSTONE SYMPOSIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-04-01 至 2014-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8527455
关键词：
Academia Address Anatomy Animal Genetics Area Arrhythmia Autophagocytosis Biological Biology Biomedical Engineering Biomedical Research Biophysics Calcium Signaling Cardiac Cardiomyopathies Cells Cellular biology Clinical Clinical Drug Development Collaborations Communities Development Developmental Biology Discipline Disease Educational workshop Environment Extracellular Matrix Functional RNA Functional disorder Genetic Heart Heart failure Human Genetics Individual Industry Knowledge Lead Mechanics MicroRNAs Modality Molecular Morbidity - disease rate Natural regeneration Outcome Patient Care Patients Physiological Proteolysis Regulation Research Role Science Scientific Advances and Accomplishments Scientist Signal Pathway Signal Transduction Stem cells Structure Students Syndrome Technology Therapeutic Therapeutic Agents Translations Utah Workplace heart function improved insight lectures meetings mortality novel novel therapeutic intervention novel therapeutics outcome forecast posters pre-clinical public health relevance symposium tissue regeneration transdifferentiation

项目摘要

DESCRIPTION (provided by applicant): Support is requested for a Keystone Symposia meeting entitled Cardiac Remodeling, Signaling, Matrix and Heart Function, organized by Anthony J. Muslin, Jil C. Tardiff and Steven R. Houser. The meeting will be held in Snowbird, Utah from April 7 - 12, 2013. The general topic of this meeting pertains to anatomic and physiologic changes that contribute to the development of heart failure and cardiac arrhythmias. More specifically, it will highlight recent scientific advances in cardiac biology and heart failur research and relate these insights to the development of novel clinical therapeutics that may impact patient care. This 4-day meeting will bring together both academic and industrial scientists employing state-of-the-art technologies encompassing the fields of stem cell science, tissue regeneration, bioengineering, non-coding RNAs, human and animal genetics, calcium signaling, autophagy and proteolysis, cardiac mechanics, and cardiac matrix biology. The translation of basic scientific discovery to pre-clinical drug development will be emphasized. In addition, there will be a workshop that details recent advances in development of novel therapeutic agents to treat heart failure and arrhythmias. This Keystone Symposia meeting is organized to provide scientists with diverse areas of expertise knowledge of technological applications and biological insights about the development and pathophysiology of cardiac dysfunction and arrhythmias. Interaction between scientists will be promoted through lectures, poster sessions, informal discussions and workshops in an environment that is highly conducive to cross-talk.

描述（由申请人提供）：请求支持由 Anthony J. Muslin、Jil C. Tardiff 和 Steven R. Houser 组织的题为“心脏重塑、信号传导、矩阵和心脏功能”的 Keystone 研讨会。该会议将于 2013 年 4 月 7 日至 12 日在犹他州斯诺伯德举行。本次会议的主题涉及导致心力衰竭和心律失常发展的解剖学和生理学变化。更具体地说，它将重点介绍心脏生物学和心力衰竭研究方面的最新科学进展，并将这些见解与可能影响患者护理的新型临床疗法的开发联系起来。这次为期 4 天的会议将汇集学术界和工业界科学家，他们采用最先进的技术，涵盖干细胞科学、组织再生、生物工程、非编码 RNA、人类和动物遗传学、钙信号传导、自噬和蛋白水解、心脏力学和心脏基质生物学。将强调基础科学发现到临床前药物开发的转化。此外，还将举办一个研讨会，详细介绍治疗心力衰竭和心律失常的新型治疗药物开发的最新进展。组织这次 Keystone 研讨会的目的是为科学家提供不同领域的专业技术应用知识以及有关心功能障碍和心律失常的发展和病理生理学的生物学见解。将通过讲座、海报会议、非正式讨论和研讨会在非常有利于交叉对话的环境中促进科学家之间的互动。