6th International Symposium on the Biology of Vertebrate Sex Determination

第六届国际脊椎动物性别决定生物学研讨会

• 批准号: 8257262
• 负责人: Richard R Behringer
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8257262
• 关键词: Amphibia; Birds; Caring; Collaborations; Communities; Congenital Abnormality; Disease; Embryonic Development; Equilibrium; Equus caballus; Family; Family suidae; Female; Fishes; Funding Applicant; Genetic; Genital system; Goat; Hawaii; Human; Hypospadias; Individual; Infertility; International; Knowledge; Learning; Malignant Neoplasms; Mammals; Marsupialia; Mus; Participant; Pathology; Postdoctoral Fellow; Process; Reagent; Reptiles; Request for Proposals; Scientist; Sex Differentiation Disorders; Sexual Development; System; Underrepresented Minority; Vertebrate Biology; Vertebrates; Woman; Work; clinically significant; comparative; disability; egg; graduate student; male; meetings; professor; programs; research study; sex determination; sperm cell; success; symposium

DESCRIPTION (provided by applicant): Funds are requested to provide partial support for the 6th International Symposium on the Biology of Vertebrate Sex Determination to be held in April of 2012. This meeting has been held at 3-year intervals since its inception in 1997. This unique meeting is attended by the entire international field working on diverse vertebrate systems including amphibians, fishes, birds, reptiles, monotremes, marsupials, and eutherian mammals, including domesticated species, mice, and humans. It is nearly impossible to keep up with the advances made in so many diverse vertebrate systems. Therefore, the objective of this meeting is to exchange information, using a comparative approach to advance our understanding of the process of sex determination and sex differentiation and disorders of sexual development. Many collaborations resulted from the first five symposia: reagents were exchanged, experiments planned and new ways of looking at sex determination discussed. Approximately 70% of the participants of the 5th symposium were junior scientists, including graduate students, postdoctoral fellows, and assistant professors, providing a unique opportunity for interactions with senior leaders in the field. We expect the 6th symposium to be as productive and stimulating as the previous ones. PUBLIC HEALTH RELEVANCE: Sexual development during embryogenesis results in the formation of males and females that produce sperm and eggs, respectively. Genetic and environmental-induced birth defects in sexual development result in clinically significant abnormalities that include intersexes, common genital abnormalities such as hypospadias, infertility, and pathologies such as cancer. The proposed conference will bring together senior and junior scientists from around the world studying different types of vertebrate animals to learn more about sexual development and apply new knowledge to the understanding and treatment of disorders of sexual development and disease.

描述（由申请人提供）：要求资金为2012年4月举行的脊椎动物性别确定生物学的第六次国际研讨会提供部分支持。自1997年成立以来，这次会议一直以3年的间隔举行。这次独特的会议由整个国际领域在包括多元化的脑电系统上工作，包括在内哺乳动物，包括驯化的物种，小鼠和人类。跟上许多多样化的脊椎动物系统的进步几乎不可能。因此，这次会议的目的是使用一种比较方法来交换信息，以促进我们对性别确定和性别差异和性发展疾病的理解。前五场研讨会引起的许多合作：交换了试剂，计划的实验以及讨论了性别确定的新方法。第五届研讨会的参与者中，约有70％是初级科学家，包括研究生，博士后研究员和助理教授，为与该领域的高级领导人互动提供了独特的机会。我们预计第六次研讨会的生产力和刺激性与以前的研讨会一样。 公共卫生相关性：胚胎发生过程中的性发育会导致分别产生精子和卵的雄性和女性的形成。性发育中的遗传和环境引起的先天缺陷导致临床上的显着异常，包括跨性别，常见的生殖器异常，例如育种，不育和癌症等病理。拟议的会议将汇集来自世界各地的高级和初级科学家，研究不同类型的脊椎动物，以了解有关性发展的更多信息，并将新知识应用于对性发展和疾病疾病的理解和治疗。