Advancing Research Operations at an Emergent R1 Minority-Serving Institution

推进新兴 R1 少数族裔服务机构的研究运作

基本信息

批准号：
10734698
负责人：
Douglas M Watts
金额：
$ 19.87万
依托单位：
UNIVERSITY OF TEXAS EL PASO
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10734698
关键词：
Achievement Animal Experimentation Animal Housing Animal Husbandry Animal Welfare Animals Biological Sciences Biology Biomedical Engineering Biomedical Research Birds Caring Censuses Communicable Diseases Controlled Environment Dedications Ecology Education Educational process of instructing Ensure Equipment Facility Designs Faculty Failure Floor Fostering Goals Growth Guidelines Health Health Disparities Research Housing IACUC Inbred BALB C Mice Inbred Strain Infrastructure Institution Institutional Policy Interdisciplinary Study Knowledge Laboratory Animals Laws Learning Life Expectancy Maintenance Malignant Neoplasms Mammals Medical Microtus Minority Minority-Serving Institution Mission Modernization Monitor Mus National Institute on Minority Health and Health Disparities Needs Assessment Neurosciences Operations Research Outcome Performance Productivity Psychology Public Health Publications Rattus Reptiles Research Research Activity Research Infrastructure Research Peer Review Research Personnel Research Project Grants Research Support Resources Rodent Services Site Students Texas Transgenic Mice Universities Water Zebrafish animal care animal facility animal resource aquarium college community engagement design expiration imaging study imaging system in vivo imaging system mouse model operation prairie vole programs repaired research study

项目摘要

Project Abstract. The University of Texas at El Paso (UTEP) is a minority-serving academic institution whose mission is dedicated to the advancement of knowledge through research, education, community engagement, as an emergent national research institution. At UTEP, there is a critical need for equipment to enhance our research infrastructure and maintain our status as an R1 institute in the years to come. and public service. Our designation as a Carnegie Tier One university "R1: Doctoral Universities – very high research activity" distinguishes UTEP As a premier biomedical research institution that is heavily engaged in promoting diversity in the scientific workforce, the proposed project will add a critically needed cage/rack washer in our Biosciences Main animal facility. The proposed request will foster our robust and productive biomedical research program involving laboratory animals. The UTEP biomedical research program is being supported by the Department of Laboratory Animal Resources Center (LARC) in partnership with the Institutional Animal Care and Use Committee (IACUC). The LARC manages and monitors the housing and use of research animals to ensure compliance with applicable Federal, State, and Local laws and guidelines as well as Institutional Policy. The LARC supports the Main animal facility in the Biosciences building, and the 3 additional animal satellite facilities in Psychology, Biology and the Interdisciplinary Research Building (IDRB). Their oversight also includes our Zebra fish aquarium as well as 2 field research stations located off of our main campus. The animal facilities are designed to accommodate exquisitely controlled environments and equipment for the maintenance and care and use of laboratory animals. In a comprehensive assessment of needs and projected growth, we identified a critical need for a cage/rack washer in the Biosciences Main animal facility. The current washer has been in use for more than 10 years, and has exceeded its 10-year life expectancy. This washer is critical to our operations because it provides sanitizing services for equipment used in the Main animal facility as well as for research involving animals housed in the Biology and Psychology animal facilities. The sanitizing services in the newly established IDRB facility is being supported by its own washer that provides services for 3 investigators and their 3 projects as well as being used as a back-up washer for the one in the Main animal facility due to frequent malfunctioning. Therefore, the requested upgraded cage/rack washer will support 39 of 42 active biomedical research projects involving the use of prairie voles (Microtus ochrogaster), mice (Mus species) BALB/c, C57/BL6 and transgenic mice, and rats (Rattus species), Sprague-Dawley and Wistar strains. The 39 projects are being conducted by 25 UTEP faculty from 5 different colleges related to public-health problems in the neurosciences, infectious diseases, cancer, and ecology and evolutionary biology, and biomedical engineering. The upgraded cage/rack washer will provide the support required to sustain the animal care and use program essential for supporting the UTEP's robust and productive biomedical research programs. 1

项目摘要德克萨斯大学埃尔帕索分校 (UTEP) 是一所为少数族裔服务的学术机构，其使命致力于通过研究、教育、社区参与来增进知识，作为一个新兴的国家研究机构，UTEP 有一个关键点。需要设备来增强我们的研究基础设施并保持我们多年来作为 R1 研究所的地位来。我们被指定为卡内基一级大学“R1：博士大学 - 非常高” 研究活动”使 UTEP 脱颖而出作为致力于促进生物多样性的一流生物医学研究机构科学劳动力，拟议的项目将在我们的生物科学中心添加急需的笼式/架式清洗机拟议的要求将促进我们强大而富有成效的生物医学研究计划，其中涉及动物设施。实验动物 UTEP 生物医学研究计划得到实验室部门的支持。动物资源中心 (LARC) 与机构动物护理和使用委员会 (IACUC) 合作。 LARC 管理和监控研究动物的饲养和使用，以确保遵守适用的规定联邦、州和地方法律和准则以及机构政策 LARC 支持主要动物。生物科学大楼内的设施，以及心理学、生物学和生物科学领域的另外 3 个动物卫星设施他们的监督还包括我们的斑马鱼水族馆和 2 个跨学科研究大楼 (IDRB)。位于我们主校区外的实地研究站旨在容纳动物设施。用于维护、护理和使用实验动物的严格控制的环境和设备。在对需求和预计增长的全面评估中，我们确定了对笼/架的关键需求 Biosciences 主要动物设施中的清洗机目前的清洗机已经使用了 10 多年，并且该洗衣机的使用寿命已超过 10 年，因为它具有消毒功能。为主要动物设施中使用的设备以及涉及饲养在动物设施中的动物的研究提供服务新设立的 IDRB 设施的生物和心理学动物设施正在进行消毒服务。由自己的洗衣机支持，为 3 位研究人员及其 3 个项目提供服务并正在使用由于经常出现故障，作为主要动物设施中的备用清洗机。所请求的升级笼/架清洗机将支持 42 个涉及使用的活跃生物医学研究项目中的 39 个草原田鼠 (Microtus ochrogaster)、小鼠 (Mus 种) BALB/c、C57/BL6 和转基因小鼠以及大鼠 (Rattus) 种）、Sprague-Dawley 菌株和 Wistar 菌株这 39 个项目由来自 5 个 UTEP 的 25 名教师进行。与神经科学、传染病、癌症和生态学等公共卫生问题相关的不同学院升级后的笼式/架式清洗机将提供支持。维持动物护理和使用计划所需的资金，这对于支持 UTEP 的稳健和富有成效至关重要生物医学研究计划。 1