FIFTH INTERNATIONAL SYMPOSIUM ON THE BIOLOGY OF VERTEBRATE SEX DETERMINATION

第五届脊椎动物性别决定生物学国际研讨会

• 批准号: 7676412
• 负责人: Richard R Behringer
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7676412
• 关键词: Amphibia; Birds; Collaborations; Congenital Abnormality; Disease; Embryonic Development; Equus caballus; Family suidae; Female; Fishes; Funding Applicant; Genital system; Goat; Human; Hypospadias; Infertility; International; Knowledge; Learning; Malignant Neoplasms; Mammals; Marsupialia; Mus; Participant; Pathology; Process; Reagent; Reptiles; Scientist; Sex Differentiation; Sexual Development; System; Vertebrate Biology; Vertebrates; Work; clinically significant; comparative; egg; male; meetings; public health relevance; research study; sex determination; sperm cell; symposium

DESCRIPTION (provided by applicant): Funds are requested to partially support the 5th International Symposium on the Biology of Vertebrate Sex Determination to be held in April of 2009. This meeting has been held at 3-year intervals since its inception in 1997. The meeting is attended by the entire international field working on diverse vertebrate systems including amphibians, fish, birds, reptiles, monotremes, marsupials, and eutherian mammals, including pigs, goats, horses, mice, and humans. As it is nearly impossible to keep up with the advances made in so many diverse systems, the objective of this meeting is to exchange information, using a comparative approach to advance our understanding of the process of sex determination and sex differentiation. A great deal of collaboration came about as a result of the first four meetings: reagents were exchanged, experiments planned and new ways of looking at sex determination discussed. Approximately, 80% of the participants of the 4th symposium were junior scientists. We expect the 5th meeting to be as productive and stimulating as the previous four. PUBLIC HEALTH RELEVANCE: Sexual development during embryogenesis results in the formation of males and females that produce sperm and eggs, respectively. Birth defects in sexual development result in clinically significant abnormalities that include intersexes, common genital abnormalities such as hypospadias, infertility, and pathologies such as cancer. The proposed conference will bring together senior and junior scientists from around the world studying different types of vertebrate animals to learn more about sexual development to apply new knowledge to the treatment of sexual disorders and disease.

DESCRIPTION (provided by applicant): Funds are requested to partially support the 5th International Symposium on the Biology of Vertebrate Sex Determination to be held in April of 2009. This meeting has been held at 3-year intervals since its inception in 1997. The meeting is attended by the entire international field working on diverse vertebrate systems including amphibians, fish, birds, reptiles, monotremes, marsupials, and eutherian哺乳动物，包括猪，山羊，马，老鼠和人类。由于几乎不可能跟上这么多不同的系统中的进步，因此本次会议的目的是使用比较方法来交换信息，以促进我们对性别确定和性别差异过程的理解。前四次会议发生了很多合作：交换了试剂，计划的实验以及讨论性别确定的新方法。大约有80％的第四届研讨会参与者是初级科学家。我们希望第五届会议与前四场会议一样富有成效和刺激。 公共卫生相关性：胚胎发生过程中的性发育会导致分别产生精子和卵的雄性和女性的形成。性发育中的出生缺陷导致临床上显着的异常，包括跨性别，常见的生殖器异常，例如杂质，不育和癌症等病理。拟议的会议将将来自世界各地的高级和初级科学家聚集在一起，研究不同类型的脊椎动物，以了解有关性发展的更多信息，以将新知识应用于治疗性疾病和疾病。