RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS

基于 FRAP 测量的体内肌动蛋白聚合率

• 批准号: 8362511
• 负责人: BORIS SLEPCHENKO
• 金额: $ 1.05万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362511
• 关键词: Actins; Biological Models; Cells; Data Analyses; Development; Funding; Grant; Measurement; Modeling; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Study models; Time; United States National Institutes of Health; base; cost; in vivo; polymerization; virtual

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The study involves determination of a rate of in vivo actin polymerization in steady-state conditions, based on FRAP measurements. This collaborative study collaborative studies involves development of cell-biological models that have potential for generalization and implementation in the Virtual Cell. Such studies, where models are necessary for data analysis and/or better qualitative understanding of cell phenomena, serve as motivators (and at the same time as testbeds) for further development of the Virtual Cell.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 该研究涉及基于FRAP测量值确定在稳态条件下体内肌动蛋白聚合的速率。这项合作研究协作研究涉及开发具有在虚拟细胞中泛化和实施潜力的细胞生物学模型。 这样的研究，对于数据分析和/或更好地对细胞现象的定性理解所需的模型，它是动机（与测试床的同时），以进一步开发虚拟细胞。