MULTIMODAL OPTICAL IMAGING INSTRUMENT AND MODEL FOR ASSESSING TARGETED THERAPIES

用于评估靶向治疗的多模态光学成像仪器和模型

• 批准号: 8362618
• 负责人: BERNARD CHOI
• 金额: $ 2.33万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362618
• 关键词: Animal Model; Biotechnology; Funding; Grant; Image; Lasers; Modeling; Monitor; National Center for Research Resources; Photochemotherapy; Principal Investigator; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; cancer therapy; cost; design; in vivo; instrument; instrumentation; novel; optical imaging; preclinical study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Our objective is to develop a unique, in vivo microvascular network animal model and dedicated imaging instrumentation to enable longitudinal preclinical studies on the efficacy of novel microvascular-targeted cancer therapies. We will design imaging instrumentation to facilitate study of anatomical and functional dynamics. Then, we will use this instrument to monitor anatomical and functional dynamics during photodynamic therapy.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 我们的目标是开发一种独特的体内微血管网络动物模型和专用成像仪器，以实现有关新型微血管靶向癌症疗法疗效的纵向临床前研究。我们将设计成像仪器，以促进研究解剖学和功能动力学。然后，我们将使用该仪器来监测光动力疗法期间的解剖学和功能动力学。