Multiscale Biophotonics: A Platform for Interdisciplinary Biomedical Research Training and Career Development

多尺度生物光子学：跨学科生物医学研究培训和职业发展的平台

• 批准号: 10508978
• 负责人: BERNARD CHOI
• 金额: $ 42.41万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-12 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10508978
• 关键词: Academia; Active Learning; Address; Applications Grants; Area; Automobile Driving; Biological Sciences; Biomedical Research; Biomedical Technology; Biophotonics; Biophysics; Biotechnology; California; Career Choice; Case Study; Code; Color; Comprehension; Computer Analysis; Computer software; Custom; Development; Development Plans; Engineering; Faculty; Federal Government; Feedback; Fellowship; Fostering; Foundations; Frequencies; Geographic Locations; Goals; Growth; Ii-Key; Individual; Industrialization; Industry; Journals; Laboratories; Leadership; Learning; Learning Module; Measurement; Measures; Medical Device; Mentors; Mentorship; Modeling; Monitor; National Institute of General Medical Sciences; Performance; Phototherapy; Postdoctoral Fellow; Problem-Based Learning; Procedures; Publications; Questionnaires; Research; Research Personnel; Research Training; Schedule; Science; Scientist; Students; Supervision; Surveys; Technology; Thinking; Time; Tissues; Training; United States National Institutes of Health; Universities; Workforce Development; biomedical scientist; career; career development; course module; data acquisition; design; early-career faculty; economic impact; evidence base; experience; experimental study; faculty research; graduate student; innovation; instrument; instrumentation; laboratory module; learning outcome; lectures; meetings; metacognition; microscopic imaging; multidisciplinary; open source; outreach; point-of-care diagnostics; programs; project-based learning; research and development; simulation software; skill acquisition; skills; symposium; technology development; technology research and development; tool; virtual

PROJECT SUMMARY The overarching objectives and specific aims of this IPERT program are to (1) prepare trainees for successful multi-disciplinary Biophotonics careers and support biomedical workforce development. This will be achieved by (2) advancing the technical and operational proficiency of our trainees in Multiscale Biophotonics through an integration of modeling, computation, experiment, and problem-based learning, and (3) providing our trainees with sustained mentorship for professional development. This will be accomplished by establishing foundational technical and operational skills in the area of Multiscale Biophotonics during a 12-day onsite short course at the University of California, Irvine. This 12-day short course utilizes an integrated modular design and evidence based learning consisting of (a) lectures, (b) technology demonstrations, (c) laboratories combining hands-on data acquisition with computational analysis using our custom Virtual Tissue Simulator (VTS) software platform, (d) Team Science training, (e) mentored capstone problem-based learning (PBL) proposal development, (f) guest lectures on the use of an interdisciplinary Biophotonics approach to address biomedical problems, (g) panel discussions on academic and industrial career paths, and (h) tours of academic and industrial facilities. Further application and growth in trainee skill development will be accomplished by a mentored capstone problem-based learning project to be pursued for one year following the short course completion. In parallel with the short course and year-long PBL project, we will offer both technical and professional mentorship. Our technical mentorship aims to support Biophotonics, instrument and measurement design, technology development, as well as modeling, computation and usage of open-source Computational Biophotonics Tools. Our professional mentorship program aims to aid trainees in identifying appropriate short- and long-term professional goals and develop strategies to attain them. The course has been designed for interdisciplinary group of graduate student, post- doctoral researcher, and faculty scientists and engineers. We propose an aggressive outreach plan to support the participation of trainees who are traditionally underrepresented within STEM as well as from geographic regions that have historically received low levels of NIH support. We aim to train up to 20 individuals each year. In summary, our program provides a technical foundation and mentoring support for trainees to advance and apply an integrated technical proficiency in Multiscale Biophotonics to solve biomedical challenges. As the integration of expertise spanning modeling, computation and experiment are in demand in biomedical research and technology development, the proposed program advances NIGMS programmatic goals for training a diverse biomedical research workforce with expertise most relevant to the NIGMS Division of Biophysics, Biomedical Technology, and Computational Biosciences.

项目摘要 该IPERT计划的总体目标和具体目标是（1）为受训者准备 成功的多学科生物素养职业并支持生物医学劳动力发展。这会 可以通过（2）提高学员在多尺度上的技术和运营水平 通过整合建模，计算，实验和基于问题的学习以及 （3）为学员提供专业发展的持续指导。这将完成 通过在多尺度生物素化领域建立基础技术和运营技能 加利福尼亚大学尔湾分校的12天现场课程。这个为期12天的短期课程利用了 集成模块化设计和基于证据的学习，包括（a）讲座，（b）技术 演示，（c）实验室使用我们的动手数据获取与计算分析相结合的实验室 定制虚拟组织模拟器（VTS）软件平台，（d）团队科学培训，（e）指导的Capstone 基于问题的学习（PBL）提案开发，（f）有关使用跨学科的来宾讲座 解决生物医学问题的生物探测方法，（g）关于学术和工业的小组讨论 职业道路，以及（H）学术和工业设施的游览。进一步的应用和成长的学员技能 开发将由一个受过指导的基于问题的学习项目来实现 短期课程完成后一年。与短期课程和为期一年的PBL项目并行 我们将提供技术和专业指导。我们的技术指导旨在支持 生物音调，仪器和测量设计，技术开发以及建模， 开源计算生物探测工具的计算和使用。我们的专业指导 计划旨在帮助受训者确定适当的短期和长期职业目标并发展 达到他们的策略。该课程是为研究生跨学科小组设计的 博士研究员，教师和工程师。我们提出了一个积极的外展计划来支持 传统在STEM和地理学中代表人数不足的受训者的参与 历史上获得低水平的NIH支持的地区。我们的目标是培训多达20个人 年。 总而言之，我们的计划为受训者提供了技术基础和指导支持 并在多尺度生物素化学中应用综合技术水平来解决生物医学挑战。作为 生物医学的需求跨越建模，计算和实验的专业知识的整合 研究与技术开发，拟议的计划促进了NIGMS计划目标 培训具有与最相关的专业知识的多样化的生物医学研究人员 生物物理学，生物医学技术和计算生物科学。