MAINTENANCE AND MONITORING OF RHESUS MONKEYS WITH TYPE-2 DIABETES

患有 2 型糖尿病的恒河猴的维护和监测

• 批准号: 8357303
• 负责人: PETER J HAVEL
• 金额: $ 7.56万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357303
• 关键词: Animals; Blood Glucose; Blood specimen; Body Weight; California; Clinical; Consumption; Diabetes Mellitus; Fructose; Funding; Future; Grant; Insulin; Macaca mulatta; Maintenance; Monitor; National Center for Research Resources; Non-Insulin-Dependent Diabetes Mellitus; Pharmaceutical Preparations; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Sampling; Source; Subcutaneous Injections; United States National Institutes of Health; cost; diabetic; pre-clinical research; research study; sugar; sweetened beverage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Genentech was supporting the maintenance and treatment of a number of diabetic rhesus monkeys at the CNPRC. The animals may be used to provide research samples for analysis or future preclinical research studies. Animals with spontaneously occurring diabetes or animals that have developed diabetes during prolonged consumption of sugar (fructose) sweetened beverages are being maintained. Blood samples are drawn for clinical monitoring, and medications (insulin) is administered by subcutaneous injection to stabilize body weight and blood glucose levels.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 Genentech支持CNPRC的许多糖尿病恒河猴的维持和治疗。这些动物可用于提供研究样本进行分析或将来的临床前研究研究。在长时间食用糖（果糖）中，患有自发发生的糖尿病或动物的动物正在维持糖尿病。 绘制血液样本以进行临床监测，并通过皮下注射来施用药物（胰岛素），以稳定体重和 血糖水平。