Biospecimen Repository - Division of Epidemiology, Statistics & Prevention Res.

生物样本库 - 流行病学、统计学部

• 批准号: 8351270
• 负责人: Germaine Louis
• 金额: $ 10万
• 依托单位: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8351270
• 关键词: Address; Age; Alabama; Aliquot; Biological Assay; Calcium; Child; Child health care; Collection; Communities; Consult; Data; Data Set; Epidemiology; Evaluation; Fetal Growth; Guidelines; Human Development; Infection; Institutes; Institutional Review Boards; Link; Longitudinal Studies; Nature; Norway; Perinatal; Policies; Pre-Eclampsia; Prevention; Prevention Research; Procedures; Qualifying; Research; Research Design; Research Personnel; Resources; Sampling; Schedule; Serum; Source; Specimen; Swab; Umbilical Cord Blood; United States National Institutes of Health; Urine; Vagina; cost; data sharing; experience; interest; premature; programs; repository; statistics; web site

The Division of Epidemiology, Statistics and Prevention Research (hereafter, Division) of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has established an internal committee, the Biospecimen Repository Access and Data Sharing Committee (BRADSC), to oversee the repository access and data sharing program. In brief, the BRADS Committee will evaluate submitted proposals for biospecimens in terms of their relevance of the study question to current research; adequacy of the study design to address the question; feasibility and appropriateness of the source study and material for conducting the new study; appropriateness of the assay, including evidence that the analyte is stable under prolonged storage; and experience of the investigators in conducting similar studies. Access to Division resources is announced on the Division website. Announcements and current proposal guidelines are available under the Research link at http://despr.nichd.nih.gov, and interested researchers should consult the Division website for resources available, the most recent guidelines for proposal submission and evaluation, and cost schedules. Procedures may vary depending on the age and nature of the samples and original institutional review board (IRB) approval, although the general outline of the procedures should remain the same. Cost schedules may vary depending on the nature and complexity of the request. The specimens and ancillary data that are currently available under this program are those from the national Collaborative Perinatal Project (CPP, 1959-1966), the Norway-Alabama Fetal Growth Study (1986-1988), the Vaginal Infections and Prematurity Study (VIP, 1984-1989), the Calcium for Preeclampsia Prevention Trial (CPEP, 1992-1997), and the Longitudinal Study of Vaginal Flora (FLORA, 1999-2002). Other collections will be made available through this mechanism in a timely fashion. The approximate number of samples available for CPP: 198,389 serum, 36,215 cord bloods; Norway-Alabama Fetal Growth Study: 14,408 serum from Alabama, 11,817 serum from Norway; VIP: 30,067 serum; CPEP: 14,429 serum, 14,331 urine; and FLORA: 12,404 serum and vaginal washes, 3,197 periodontal swabs. Multiple aliquots are available for most samples.

Eunice Kennedy Shriver国家儿童健康与人类发展研究所（NICHD）的流行病学，统计与预防研究（以下简称，以下简称，部门）成立了一个内部委员会，即生物测试存储库访问和数据共享委员会（BRADSC），以监督重建访问和数据共享计划。简而言之，布拉德斯委员会将根据研究问题与当前研究的相关性评估提交的生物测量提案；研究设计的充分性来解决这个问题；来源研究的可行性和适当性，以及进行新研究的材料；该测定法的适当性，包括证据表明该分析物在长时间存储下是稳定的；和研究人员进行类似研究的经验。 在部门网站上宣布了对部门资源的访问。可以在http://despr.nichd.nih.gov的研究链接下获得公告和当前的提案准则，感兴趣的研究人员应咨询该部门的可用资源，最新的提案提交和评估指南以及成本时间表。 尽管程序的一般概述应保持不变，但程序可能会根据样品的年龄和性质和原始机构审查委员会（IRB）批准而有所不同。费用时间表可能会因请求的性质和复杂性而有所不同。 The specimens and ancillary data that are currently available under this program are those from the national Collaborative Perinatal Project (CPP, 1959-1966), the Norway-Alabama Fetal Growth Study (1986-1988), the Vaginal Infections and Prematurity Study (VIP, 1984-1989), the Calcium for Preeclampsia Prevention Trial (CPEP, 1992-1997), and the Longitudinal Study阴道菌群（Flora，1999-2002）。 其他收藏将通过这种机制及时提供。 可用于CPP的样品的大约数量：198,389血清，36,215条脐带血；挪威 - 阿拉巴马胎儿生长研究：来自阿拉巴马州的14,408血清，挪威11,817血清； VIP：30,067血清； CPEP：14,429血清，14,331尿；和植物群：12,404种血清和阴道洗涤，3,197个牙周拭子。 大多数样品可用多个等分试样。