The University of Rochester Clinical and Translational Science Institute

罗彻斯特大学临床与转化科学研究所

基本信息

批准号：
8259882
负责人：
THOMAS Arthur PEARSON
金额：
$ 50万
依托单位：
UNIVERSITY OF ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-30 至 2012-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8259882
关键词：
Academic Medical Centers Award Biomedical Research Centers of Research Excellence Clinical Clinical Research Clinical Sciences Clinical Trials Clinical and Translational Science Awards Collaborations Communities Community Health Centers Consultations Data Dentistry Development Dimensions Discipline Discipline of Nursing Education Educational Curriculum Evaluation Faculty Fostering Funding Goals Home environment Human Incubators Individual Institutes Institution K-Series Research Career Programs Leadership Maintenance Measurement Medical center Methodology Methods Modeling New York Outcome Participant Performance Pilot Projects Rejuvenation Reporting Research Research Personnel Resources School Nursing Services System Technology Therapeutic Training Programs Training and Education Translational Research Translations Universities Vision career development clinical practice comparative effectiveness effectiveness research evidence base implementation research innovation meetings novel programs public health relevance public-private partnership response university student

项目摘要

DESCRIPTION (provided by applicant): The Rochester Clinical and Translational Science Award (RCTSA) Program proposes continuation of its dual goals: 1) To organize, support, and expand clinical and translational research at the University of Rochester within an academic home, the University of Rochester Clinical and Translational Science Institute (UR-CTSI), and 2) To integrate and collaborate with regional and national institutions to expand a National Clinical and Translational Research Network. The RCTSA Program has truly transformed the University of Rochester Medical Center (URMC), with the construction of a state-of-the-art Clinical and Translational Science Building, the integration of clinical and translational science into the shared vision for URMC research, a successful system of dynamic governance, expansion of research resources, and enthusiastic participation and leadership in the National CTSA Consortium. To continue this momentum, the UR-CTSI will carry out a number of specific aims. First, three new key functions will be implemented: Public-Private Partnerships, T1 Translation, and Comparative Effectiveness Research. Existing Key Functions will be reorganized and consolidated to provide better support of investigators by an expanded Office of Regulatory Support, a Navigator/Consultation Service, and an Incubator Program consolidating Pilot Studies, Novel Methodologies, and Translational Technologies Key Functions. The CTSI will establish and foster four centers of research excellence across the spectrum of research translation: Center for Human Experimental Therapeutics (T1 Research); Clinical Research Center (T1-3 Research); Center for Research Implementation and Translation (T2-3 research under School of Nursing sponsorship); and Center for Community Health (T2-3 research). A broad range of education, training, and career development programs will continue to meet research workforce needs. The UR-CTSI will be an active participant in the National CTSA consortium with sharing of expertise, methods, data, and curricula. The Upstate New York Translational Research Network (UNYTRN) will be expanded to support the region's biomedical research institutions. Finally, the UR-CTSI will be evaluated through the measurement of rigorous performance outcomes. PUBLIC HEALTH RELEVANCE (provided by applicant): The UR Clinical and Translational Science Institute (UR-CTSI) will be the focal point for translation of basic discoveries to human applications and clinical trials, and for evidence-based implementation of efficacious clinical practices and effective community strategies. The UR-CTSI will be a model for CTSA involvement of nursing, dentistry, and other disciplines, for engagement of the Rochester community in all aspects of research and for collaboration with regional biomedical institutions in research translation.

DESCRIPTION (provided by applicant): The Rochester Clinical and Translational Science Award (RCTSA) Program proposes continuation of its dual goals: 1) To organize, support, and expand clinical and translational research at the University of Rochester within an academic home, the University of Rochester Clinical and Translational Science Institute (UR-CTSI), and 2) To integrate and collaborate with regional and national institutions to expand a National Clinical and Translational Research Network. RCTSA计划确实通过建立了最先进的临床和转化科学大楼，将临床和转化科学的整合到URMC研究的共同愿景，一种动态治理的共同愿景，研究资源的扩展以及在国家ctsa Consort的热情参与和领导力的系统中，真正改变了罗切斯特大学医学中心（URMC），临床和转化科学的一体化为URMC研究的共同愿景。为了继续这一势头，UR-CTSI将执行许多具体的目标。首先，将实施三个新的关键功能：公私伙伴关系，T1翻译和比较有效性研究。现有的关键功能将通过扩大的监管支持办公室，导航员/咨询服务以及孵化器计划（合并试点研究，新颖的方法论和转化技术的关键功能）进行重新组织和合并，以提供调查人员的更好支持。 CTSI将在整个研究翻译中建立并培养四个卓越研究中心：人类实验疗法中心（T1 Research）；临床研究中心（T1-3研究）；研究实施与翻译中心（在护理学院赞助学校下的T2-3研究）；和社区卫生中心（T2-3研究）。广泛的教育，培训和职业发展计划将继续满足研究人员需求。 UR-CTSI将是国家CTSA联盟的积极参与者，并共享专业知识，方法，数据和课程。纽约北部转化研究网络（UNTRN）将扩展以支持该地区的生物医学研究机构。最后，将通过测量严格的性能结果来评估UR-CTSI。公共卫生相关性（由申请人提供）：UR临床和转化科学研究所（UR-CTSI）将成为将基本发现转化为人类应用和临床试验的重点，以及基于证据的有效临床实践和有效的社区战略的实施。 UR-CTSI将是CTSA参与护理，牙科和其他学科的模型，用于在研究的各个方面以及与区域生物医学机构在研究翻译中的各个方面的参与。

项目成果

期刊论文数量（155）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Variable Selection for Sparse High-Dimensional Nonlinear Regression Models by Combining Nonnegative Garrote and Sure Independence Screening.

DOI：
10.5705/ss.2012.316
发表时间：
2014-07
期刊：
Statistica Sinica
影响因子：
1.4
作者：
Wu S;Xue H;Wu Y;Wu H
通讯作者：
Wu H

Generalized Ordinary Differential Equation Models.

DOI：
10.1080/01621459.2014.957287
发表时间：
2014-10
期刊：
Journal of the American Statistical Association
影响因子：
3.7
作者：
Miao H;Wu H;Xue H
通讯作者：
Xue H

A pilot study to enhance preventive asthma care among urban adolescents with asthma.

DOI：
10.3109/02770903.2011.576741
发表时间：
2011-06
期刊：
The Journal of asthma : official journal of the Association for the Care of Asthma
影响因子：
0
作者：
Halterman JS;Riekert K;Bayer A;Fagnano M;Tremblay P;Blaakman S;Borrelli B
通讯作者：
Borrelli B

Depressive symptoms are associated with allostatic load among community-dwelling older adults.