Center for Native Population Health Disparities

土著人口健康差异中心

• 批准号: 8299111
• 负责人: DEDRA S BUCHWALD
• 金额: $ 201.12万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8299111
• 关键词: Address; Adult; American Indian and Alaska Native; American Indians; Basic Science; Behavioral Sciences; Biological; Biological Sciences; Businesses; Caliber; Cancer Survivorship; Centers for Population Health; Child; Clinical Sciences; Clinical assessments; Communities; Community Actions; Databases; Employee Strikes; Enrollment; Ensure; Epidemiology; Ethnic Origin; Funding; Genetic; Genetic Predisposition to Disease; Health; Institute of Medicine (U.S.); Intervention; Investigation; Life Expectancy; Link; Longevity; Malignant Neoplasms; Mental Health; Modeling; Native-Born; Outcome; Patients; Population; Primary Prevention; Principal Investigator; Publications; Quality of life; Race; Reporting; Request for Applications; Research; Research Personnel; Rivers; Role; Rural Population; Science; Scientist; Secondary Prevention; Seminal; Sioux Indians; Site; Social Sciences; Surgeon; Tribes; Underserved Population; United States National Institutes of Health; Universities; Washington; Work; base; cancer health disparity; career development; community based participatory research; experience; health disparity; improved; member; population health; programs; psychosocial; sociologist; theories; tribal community

DESCRIPTION (provided by applicant): This application responds to RFA-CA-09-001, which requests applications for Centers for Population Health and Health Disparities (CPHHD) that will collaborate with other such Centers to promote transdisciplinary research in health disparities. In this application, the University of Washington (UW) and Black Hills Center for American Indian Health (BHCAIH) seek support for a Center for Native Population Health Disparities (CNPHD). Our aim is to directly contribute to improved cancer health outcomes and quality of life for American Indian/Alaska Native (AI/AN) populations - populations that are experiencing dramatic health inequities. Although strides have been made in improving health and life expectancy in Native communities, much work remains, as eloquently argued in the Institute of Medicine report, Examining the Heath Disparities Research Plan of the National Institutes of Health: Unfinished Business'^ and the Surgeon General's report. Mental Health: Culture, Race, and Ethnicity.^ Our CNPHD will strive to address the gaps identified in these seminal publications. Our research agenda articulates a model for AI/AN health and health disparities that is well-grounded in current theory, consistent with that of the CPHHDs, and applicable to all our projects. The many Native people involved in this Center, as well as our Community Action Board and 2 AI/AN sociologists, will help us critically examine the role of culture in the model. Our investigations reiterate a single leitmotif - the examination of genetic, environmental, biological, psychosocial, and cultural influences on cancer health disparities at multiple levels and across the lifespan. Our projects include children, youth, and adults. The proposed CNPHD will fill a striking research gap, since none of the 8 currently funded CPHHDs examines AI/AN health disparities and only 1 targets rural populations. Our Center will truly represent our research partner communities, with 11 AI/ANs serving in Icey roles, for example as Project and Core Leaders or Co-investigators (see Table 5 at end). Most notably, the Co-Principal Investigator is an enrolled member of the Cheyenne River Sioux Tribe and directs a community-based organization. As a result, all proposed projects have deep and meaningful ties to their respective communities. The unique connection between our investigators and the tribal communities imbues our work with a special dynamic. Investigators are more fully invested in the communities with which they work, and this commitment goes a long way to ensuring reciprocity and respect among ail parties involved in the research. Finally, the CNPHD will truly be transdisciplinary. We bring together scholars from across the full spectrum of biological, social, and behavioral sciences. Of special note, we do not limit "team science" to traditional academic circles, but bring in ideas and Native expertise from community-based leaders and entities. We envision that this approach will eventually move research on AI/AN health disparities beyond the purely descriptive into meaningful action. The CNPHD will pursue an integrated, multi-faceted research program that capitalizes on several large, well-organized, existing efforts and databases, as well as numerous well-established and mutually respectful relationships, to address issues in the genetics, etiology, epidemiology, primary and secondary prevention, clinical assessment, treatment, and survivorship of cancer. Clinical, basic, and social sciences are linked with a community-based participatory perspective to provide a transdisciplinary research program of the highest scientific and programmatic caliber for AI/AN community members, patients, clinicians, researchers, and health decision-makers. Notably, this application follows the overarching requirements for CPHHDs to 1) include scientists from basic, clinical, and social sciences; 2) focus on an underserved population; 3) incorporate principles of community-based participatory research; 4) include interventions directed towards at least 2 levels; 5) offer career development opportunities; and 6) interact and harmonize with other CPHHDs and NIH program staff to conduct transdisciplinary, multi-site, highly interactive research.

描述（由申请人提供）：本申请对RFA-CA-09-001做出响应，该申请要求针对人口健康和健康差异中心（CPHHD）申请，该申请将与其他此类中心合作，以促进健康差异的跨学科研究。在此申请中，华盛顿大学（UW）和黑山印第安人卫生中心（BHCAIH）寻求支持本地人口健康差异中心（CNPHD）的支持。我们的目的是直接为美洲/阿拉斯加本地人（AI/AN）人群的改善癌症健康成果和生活质量做出贡献 - 患有急剧健康不平等的人群。尽管在改善本地社区的健康和预期寿命方面取得了长足的进步，但正如医学研究所报告中雄辩地所论证的那样，仍在研究国立卫生研究院的荒地差异研究计划：未完成的企业^和外科医生的报告。心理健康：文化，种族和种族。^我们的CNPHD将努力解决这些开创性出版物中确定的差距。 我们的研究议程阐明了AI/A/A/A的健康和健康差异的模型，该模型在当前理论中与CPHHD相一致，并且适用于我们所有项目的模型。参与该中心的许多土著人民以及我们的社区行动委员会和2个AI/A A/A A/A A A/A A A/A A A/A A A/A AN，将有助于我们批判性地研究文化在模型中的作用。我们的调查重申了一个单一的leitmotif-检查遗传，环境，生物学，心理社会和文化对多个层次以及整个寿命的癌症健康差异的影响。我们的项目包括儿童，青年和成人。拟议的CNPHD将填补明显的研究差距，因为目前的8个CPHHDS都没有检查AI/A A A/A AN健康差异，只有1个目标是农村人口。我们的中心将真正代表我们的研究合作伙伴社区，其中有11个AI/ANS担任冰块角色，例如项目和核心领导者或共同研究员（请参阅最后的表5）。最值得注意的是，联合院长调查员是Cheyenne River Sioux部落的入学成员，并指导一个社区组织。结果，所有拟议的项目都与各自社区都有牢固而有意义的联系。我们的调查人员与部落社区之间的独特联系使我们的工作充满了特殊的动态。调查人员在与他们合作的社区中更全面投入，这一承诺对于确保参与研究的各方之间的互惠和尊重有很长的路要走。最后，CNPHD将真正是跨学科的。我们将来自各种生物，社会和行为科学的学者汇集在一起​​。特别值得注意的是，我们不会将“团队科学”限制在传统的学术界，而是引入社区领导者和实体的想法和本地专业知识。我们设想，这种方法最终将使对AI/A A的健康差异的研究将纯粹的描述性的研究转变为有意义的行动。 CNPHD将追求一项综合的，多面的研究计划，该计划在几个大型，组织良好的现有工作和数据库以及许多建立良好和相互尊重的关系上都有利用，以解决遗传学，病因学，流行病学，初级和次要预防，临床评估，治疗，治疗，治疗，临床评估，临床评估，临床评估，临床评估，临床评估，生存。临床，基础和社会科学与基于社区的参与式观点有关，为AI/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A/A AN社区成员，患者，临床医生，研究人员和健康决策者提供跨学科研究计划。值得注意的是，该应用遵循CPHHD的总体要求至1）包括基础，临床和社会科学的科学家； 2）专注于服务不足的人群； 3）纳入基于社区的参与性研究原则； 4）包括针对至少2个级别的干预措施； 5）提供职业发展机会； 6）与其他CPHHD和NIH计划人员进行互动和协调，以进行跨学科的多站点，高度互动的研究。