Administrative Core

行政核心

基本信息

批准号：
10667528
负责人：
DEDRA S BUCHWALD
金额：
$ 50.59万
依托单位：
WASHINGTON STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2026-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10667528
关键词：
Advisory Committees Alaska Native Alzheimer&apos s Disease Alzheimer&apos s disease related dementia American Indians Appointment Articulation Biology Budgets Businesses Clinical Trials Data Monitoring Committees Collaborations Collection Communication Communities Community Actions Computers Doctor of Philosophy Education Ensure Evaluation Faculty Genetic Goals Hawaii Health Health care facility Human Resources Institution Institutional Review Boards International Leadership Medicine Mental Health Minnesota Minority Groups Mission Monitor National Institute on Aging Native Hawaiian Native Hawaiian or Other Pacific Islander Neurology Oral Pacific Islander Policies Population Research Preparation Principal Investigator Process Publications Regulation Research Research Activity Research Methodology Research Personnel Research Project Grants Research Support Rural Satellite Centers Scholarship Scientist Site Specialist Travel Tribes Underrepresented Minority Underrepresented Populations Underserved Population Universities Washington Work Writing brain health career development college community organizations data sharing experience health disparity implementation facilitation meetings operation outreach physical conditioning professor programs recruit urban Native American

项目摘要

ADMINISTRATIVE CORE: ABSTRACT Natives Engaged in Alzheimer’s Research (NEAR) will be organized into an Administrative Core, a Recruitment and Engagement Core, a Biospecimen Core, a Research Methods Core, and 3 Research Projects. We will also incorporate a nationwide network of 8 Satellite Centers led by American Indian/Alaska Native and Native Hawaiian/Pacific Islander investigators who will assist with outreach, recruitment, and biospecimen collection. The contact Principal Investigator and Administrative Core Leader of NEAR, Dedra Buchwald, MD, Professor of Medicine at Washington State University, is widely recognized for her research, experience, and leadership in Alzheimer’s disease and related dementias in Native communities, and for her ongoing efforts to eliminate health disparities. She is the Founding Director of Partnerships for Native Health, a program of culturally appropriate research that has established 150+ partnerships with various Native entities in a 15-state region, including tribes, Indian health facilities, and organizations serving American Indians, Alaska Natives, Native Hawaiians, and Pacific islanders. Dr. Buchwald will be joined by James Galvin, MD, MPH, Professor, University of Miami, who will serve as the Scientific Director of NEAR and as a Multiple Principal Investigator and by John Kauwe, PhD, who will also serve as a Multiple Principal Investigator and as Co-Leader of the Biospecimen Core. This Core will integrate the contributions of 6 academic partner institutions, all of which have experience collaborating with American Indian/Alaska Native and Native Hawaiian/Pacific Islander, and other underrepresented minority populations, and with strengths in administration, research methods, scholarship, community-informed research, field work, and dissemination. Notably, our 3 Research Projects include 11 tribes, 7 urban Indian programs, an AI-owned small business, and 5 Native Hawaiian-serving community organizations. Our Specific Aims are to: 1) Support logistical and field operations across academic sites, including coordination of meetings and travel, and facilitate interactions with the Satellite Centers; 2) Oversee a plan for management, organization, and communication that stimulates, coordinates, integrates, and monitors activities and functions across and among all NEAR Research Projects, Cores, faculty, and institutions; 3) Supervise and facilitate implementation of key strategic decisions, research regulatory processes, and data sharing plans; 4) Collaborate on program planning, review, and evaluation to ensure that NEAR achieves its goals and maintains its focus on population-based research in Alzheimer’s disease and related dementias-related health disparities; and 5) Convene the Executive Committee, the External Advisory Committee, the Publications and Presentations Committee, the Data Safety and Monitoring Board, and the Community Action Board. The latter will include diverse stakeholders and guide researchers on local cultural concerns and solutions. In summary, the Administrative Core will manage, coordinate, and supervise the entire range of activities; monitor progress; ensure that component plans are implemented; and verify that all NEAR-supported research is carried out in compliance with Federal regulations and policies. Together, NEAR committees and activities will ensure the successful implementation of all efforts.

行政核心：摘要从事阿尔茨海默氏症研究（接近）的当地人将被组织成一个行政核心，招聘和参与核心，生物循环核心，研究方法核心和3个研究项目。我们也会在美国印第安人/阿拉斯加本地人领导的8个卫星中心的全国性网络中夏威夷/太平洋岛民的调查人员将协助推广，招募和生物群体收集。联系主要调查员兼行政核心领导人，Dedra Buchwald，医学博士，教授华盛顿州立大学的医学因其研究，经验和领导而受到广泛认可阿尔茨海默氏病和当地社区的相关痴呆症，以及为了消除健康的持续努力差异。她是本地健康合作伙伴关系的创始董事，这是一项适当的文化计划与15个州的各个本土实体建立了150多个伙伴关系的研究，包括部落，印度卫生设施以及为美洲印第安人，阿拉斯加土著人，夏威夷原住民和太平洋岛民。 Buchwald博士将由MD，MPH，MPH，迈阿密大学教授的詹姆斯·加尔文（James Galvin）加入，他将加入将担任近亲和多个首席研究员的科学总监，并由约翰·考韦（John Kauwe）博士担任他还将担任多个主要研究员，并担任Biospecimen Core的共同领导者。这个核心将整合6个学术合作伙伴机构的贡献，所有这些都有与之合作的经验美洲印第安人/阿拉斯加本地人和夏威夷人/太平洋岛民以及其他代表不足的少数民族人口，并具有管理，研究方法，科学，社区信息研究的优势，现场工作和传播。值得注意的是，我们的3个研究项目包括11个部落，7个城市印度计划， AI拥有的小型企业和5个夏威夷当地的社区组织。我们的具体目标为：1）支持跨学术站点的后勤和现场运营，包括会议协调和旅行，并促进与卫星中心的互动； 2）监督管理，组织和刺激，坐标，集成和监视各种活动和功能的沟通所有附近的研究项目，核心，教职员工和机构； 3）监督和促进密钥的实施战略决策，研究监管过程和数据共享计划； 4）合作计划计划，审查和评估以确保近乎实现其目标并保持关注基于人群的目标关于阿尔茨海默氏病和与痴呆症相关的健康差异的研究； 5）召集高管委员会，外部咨询委员会，出版物和演示委员会，数据安全和监视委员会和社区行动委员会。后者将包括潜在利益相关者和指南有关当地文化关注和解决方案的研究人员。总而言之，行政核心将管理协调并监督整个活动范围；监视进度；确保组件计划是实施的;并验证所有近乎支持的研究均根据联邦法规进行和政策。近乎委员会和活动将共同确保成功实施所有努力。