2011 Cold Spring Harbor Conference on Neurobiology of Drosophila

2011年冷泉港果蝇神经生物学会议

• 批准号: 8201856
• 负责人: DAVID J. STEWART
• 金额: $ 1.5万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8201856
• 关键词: Accounting; Address; Animal Model; Animals; Area; Asians; Automobile Driving; Behavior; Behavioral; Biochemistry; Biological; Biological Models; Brain; Brain Diseases; Businesses; Cells; Cellular biology; Circadian Rhythms; Collaborations; Complex; Data; Development; Disease; Disease model; Doctor of Philosophy; Drosophila genome; Drosophila genus; Drosophila melanogaster; Electrophysiology (science); Ensure; Environment; European; Event; Evolution; Faculty; Fostering; Future; Genes; Genetic; Goals; Health; Human; Image; International; Laboratories; Length of Stay; Maintenance; Mammals; Molecular; Molecular Biology; Nervous System Physiology; Nervous system structure; Neurobiology; Neurons; Neurosciences; Oral; Participant; Physiological; Postdoctoral Fellow; Published Comment; Questionnaires; Research; Research Institute; Research Personnel; Research Technics; Schedule; Science; Scientist; Senior Scientist; Series; Synaptic Transmission; System; Techniques; Transcriptional Regulation; Vertebrates; Voting; Woman; Work; Writing; abstracting; base; fly; graduate student; insight; interest; laboratory facility; lectures; meetings; nervous system disorder; neural circuit; neurodevelopment; posters; relating to nervous system; sensory system; success; symposium; technological innovation; translational study; unpublished works

DESCRIPTION (provided by applicant): The planned conference on Neurobiology of Drosophila will convene a group of junior and senior scientists to discuss the latest advances in the neurobiology research that are being made in the highly successful model system the fruit fly Drosophila melanogaster. This proposal seeks support for the 2011 conference, which is the 14th biennial international meeting in this series. This meeting focuses on advances made using the combined power of genetics, molecular biology, biochemistry, cell biology, electrophysiology, imaging, and behavioral analysis to address fundamental issues in neurobiology. The topics covered will range from i) Sensory systems: ii) Behavior, brain function & its evolution; iii) Neurological disease models & cellular mechanisms; iv) Neural circuits - development, evolution and function; v) Synaptic transmission, development and plasticity; vi) Neural development & evolution; and vii) Technological innovations & applications. By vote of the previous participants, the meeting will remain of moderate size (430 participants) and will have no parallel sessions so as to facilitate discussion, exchange of ideas and techniques, and to promote new collaborations in this rapidly-evolving field. All applicants will be encouraged to submit an abstract and the majority of participants will present a talk or poster. Speakers will be chosen by session leaders and meeting organizers from the most timely and interesting abstracts submitted a few months in advance of the conference: this will ensure that late-breaking science is covered in all of the talks. In the event that the conference is oversubscribed, participants will be chosen to include at least one representative from each participating laboratory. This conference has an excellent track record for highlighting the work of younger investigators and women. To encourage participation by junior investigators, a special lecture is presented by a graduate student who has written the best Ph.D. thesis since the previous meeting. PUBLIC HEALTH RELEVANCE: This Neurobiology of Drosophila conference focuses on advances made using the combined power of genetics, molecular biology, biochemistry, cell biology, electrophysiology, imaging, and behavioral analysis to address fundamental issues in neurobiology using the model organism Drosophila melanogaster. A driving principle of the entire field is that the lowly fruit fly, while seeming to have little in common with humans, shares many of the same genes, molecules and neural wiring -albeit far simpler - with vertebrate animals. Building on one hundred years of research in fly genetics, the fly neurobiology field is a burgeoning field of endeavor with many laboratories around the world making significant advances in the field. Understanding how these systems work in Drosophila has enormous relevance to our efforts to elucidate how these things function in higher animals, with consequences including how we think about neurological disease, brain evolution and other major themes of research in humans. Many of the research techniques that are developed for use in the fly have considerable utility in research into nervous system function in vertebrates and mammals. The aim of the conference is to provide a forum to bring together a diverse group of scientists working in different areas of the field of fly neurobiology. The meeting will be of moderate size and will have no parallel sessions so as to facilitate discussion, exchange of ideas and techniques, and to promote new collaborations in this rapidly evolving field. The scientific organizers are elected by vote of the previous participants, thus ensuring a fresh perspective on the scientific exchange. All applicants are encouraged to submit an abstract and the majority of participants will present a talk or poster. Speakers will be chosen by session leaders and the meeting organizers from the most timely and interesting abstracts submitted a few months in advance of the conference, ensuring that late-breaking science is covered in all of the talks.

描述（由申请人提供）：计划举行的果蝇神经生物学会议将召集一组初级和高级科学家，讨论在非常成功的果蝇模型系统果蝇中取得的神经生物学研究的最新进展。该提案寻求 2011 年会议的支持，这是该系列的第 14 次双年度国际会议。本次会议重点讨论利用遗传学、分子生物学、生物化学、细胞生物学、电生理学、成像和行为分析的综合力量来解决神经生物学的基本问题所取得的进展。涵盖的主题范围包括：i) 感觉系统：ii) 行为、大脑功能及其进化； iii) 神经疾病模型和细胞机制； iv) 神经回路——发育、进化和功能； v) 突触传递、发育和可塑性； vi) 神经发育和进化； vii) 技术创新与应用。经往届与会者投票，会议将保持适度规模（430人），并且不会举行平行会议，以促进讨论、思想和技术的交流，并促进这个快速发展的领域的新合作。我们鼓励所有申请人提交摘要，大多数参与者将发表演讲或海报。演讲者将由会议领导人和会议组织者从会议前几个月提交的最及时、最有趣的摘要中选出：这将确保所有演讲都涵盖最新的科学。如果会议报名人数超额，将选择参与者中至少包括来自每个参与实验室的一名代表。这次会议在突出年轻研究人员和女性的工作方面有着出色的记录。为了鼓励初级研究人员参与，由撰写了最好的博士论文的研究生进行了一次特别讲座。自上次会议以来的论文。 公共健康相关性：本次果蝇神经生物学会议重点讨论利用遗传学、分子生物学、生物化学、细胞生物学、电生理学、成像和行为分析的综合力量所取得的进展，以利用模式生物果蝇解决神经生物学的基本问题。整个领域的一个驱动原理是，低等果蝇虽然看起来与人类没有什么共同点，但与脊椎动物有许多相同的基因、分子和神经线路——尽管简单得多。建立在一百年的果蝇遗传学研究的基础上，果蝇神经生物学领域是一个新兴的领域，世界各地的许多实验室在该领域取得了重大进展。了解这些系统在果蝇中的工作原理对于我们阐明这些系统在高等动物中如何发挥作用的努力具有巨大的相关性，其后果包括我们如何看待神经系统疾病、大脑进化和人类研究的其他主要主题。许多为果蝇开发的研究技术在脊椎动物和哺乳动物神经系统功能的研究中具有相当大的实用性。会议的目的是提供一个论坛，将在果蝇神经生物学领域不同领域工作的不同科学家群体聚集在一起。会议规模适中，不设平行会议，以促进讨论、思想和技术交流，并促进这一快速发展领域的新合作。科学组织者由往届参与者投票选出，从而确保科学交流的新视角。我们鼓励所有申请人提交摘要，大多数参与者将发表演讲或海报。演讲者将由会议领导人和会议组织者从会议前几个月提交的最及时、最有趣的摘要中选出，以确保所有演讲都涵盖最新的科学知识。