BIOSTATISTICS AND INFORMATICS

生物统计学和信息学

基本信息

批准号：
8181004
负责人：
SUSAN G. HILSENBECK
金额：
$ 22.06万
依托单位：
BAYLOR COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-17 至 2015-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8181004
关键词：
Address Adult Architecture Area Basic Science Bioinformatics Biological Markers Biology Biometry Biostatistics Shared Resource Breast Cancer Center Cancer Center Support Grant Cancer Grant Supplements (P30)Capital Cellular biology Chad Charge Childhood Clinical Clinical Data Clinical Research Clinical Trials Collaborations Commit Common Data Element Communities Complex Computer software Conduct Clinical Trials Conflict of Interest Contracts DNA Sequence Data Data Analyses Data Base Management Databases Development Discipline Doctor of Philosophy Educational process of instructing Equipment Evaluation Experimental Designs Faculty Fellowship Flow Cytometry Shared Resource Funding Funding Agency Future Genomics Goals Grant Guidelines Human Resources Informatics Information Management Journals Laboratories Laboratory Study Leadership Left Link Malignant Neoplasms Management Information Systems Medical Medicine Methodology Methods Microscopy Mission Molecular Molecular Medicine Monitor Names Nuclear Receptors Paper Pathology Pediatrics Phase II Clinical Trials Play Police Population Sciences Postdoctoral Fellow Preparation Process Production Prostate Published Comment RNA Interference Recording of previous events Recovery Recruitment Activity Reporting Reproduction spores Research Research Infrastructure Research Personnel Research Project Grants Research Support Resource Sharing Resources Review Committee Role Schedule Schools Scientist Screening procedure Services Source Statistical Data Interpretation Strategic Planning Students Supervision System Time Tissue Banking Tissue Banks Training Training Programs Training and Education United States National Institutes of Health Vendor Vocabulary Work anticancer research base cancer Biomedical Informatics Grid cancer cell cancer prevention college cost cost effective data management data mining data sharing design epigenomics experience gene therapy genome-wide high throughput technology improved informatics shared resource interest interoperability meetings member new technology next generation novel strategies oncology open source programs protein expression research study skills tool working group

项目摘要

Biostatistics shared resources have, from the beginning of cancer centers, been a centerpiece of the infrastructure that underpins and adds value to a cancer center. The same holds true today, although needs continue to evolve. At present, within the Dan L Duncan Cancer Center, the Biostatistics and Informatics Shared Resource plays a critical role, and going forward into the next funding period, we propose changes and strategic enhancements that will continue to provide the best possible support of research at the Cancer Center. The resource was initially established as part of the first CCSG application in 2006. The Resource grew, primarily, out of existing capabilities and personnel in the biostatistics group in the Breast Center. Directed by Dr. Susan Hilsenbeck, this group had already established strong grant-funded collaborations with non-Breast Center investigators in what is now the Cancer Cell and Gene Therapy Program, the Nuclear Receptors Program, and the Cancer Prevention and Population Science Program, as well as a broad spectrum of investigators in the Breast Program. During our first funding period we continued to grow strategically, adding faculty, staff and services, according to the plan put forward in our initial application, and to address Cancer Center needs. We first added faculty and staff to increase support for bioinformatic analyses. We expanded expertise to support clinical trials, and now, in this competing renewal, propose to formally add support for other kinds of informatics by inclusion of the Cancer Center's developing informatics group. The primary purpose of the Resource is to support the research efforts of Cancer Center investgators through collaboration on biostatistical and informatic aspects of design, conduct, analysis, and interpretation of clinical and basic science studies. This will be accomplished by providing biostatistical and bioinformatic assistance (general consultation, experimental design, assistance with conduct of clinical trials, statistical analysis, methodologic development and interpretation); informatic support (project management, IT/hardware management, and database development including caBlG integration); statistical review for PRMS and education and training. Future plans include additional faculty and staff recruitment, development of better systems for clinical data management and reporting, and assisting high throughput technology-oriented share-resources, such as the Integrated Microscopy SR or the new Genome-Wide RNAi Screening and Analysis SR, with improved data management and analysis pipelines.