Biostatistics & Clinical Research Core

生物统计学

• 批准号: 10427343
• 负责人: SUSAN G. HILSENBECK
• 金额: $ 10.08万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-25 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10427343
• 关键词: AIDS/HIV problem; Africa South of the Sahara; Biometry; Clinical Research; Comprehensive Cancer Center; Computer software; Data; Data Security; Databases; Documentation; Ensure; Ethics; Health Sciences; Individual; Information Retrieval; International; Laboratories; Medicine; Monitor; Pathologic; Pilot Projects; Public Health Schools; Reporting; Research; Research Design; Research Project Grants; Resource Sharing; Sample Size; Science; Services; Statistical Data Interpretation; Universities; Update; Work; college; data management; data quality; design; experimental study; improved; infection related cancer; lecturer; pediatric human immunodeficiency virus; professor; quality assurance

Pediatric HIV/AIDS & Infection-Related Malignancies Research Consortium for Sub-Saharan Africa (PARCA): Biostatistics & Clinical Research Core (Core C) The responsibilities of the Biostatistics & Clinical Research Core (Core C) include support of the individual projects and other cores, as well as the overall data management for the Consortium as a whole. To accomplish these objectives, the Aims of the Biostatistics & Clinical Research Core are: 1. Data Management: To maintain relevant databases, administer data quality assurance, data security and backups, provide and facilitate information retrievals and reports, monitor the progress of all studies, update hardware and software, provide and improve documentation. 2. Design of Studies and Experiments: To work with all projects and cores to develop appropriate study designs, analytic plans, and sample size estimations and determine feasibility for the pilot projects. 3. Statistical Analyses: To analyze data produced by the Projects and Cores in accordance with the analytic plans generated in Aim 2. 4. Quality Assurance and Regulatory Compliance: To conduct analyses to ensure the quality of the data collected or generated by laboratory and pathological analyses of biospecimens; to ensure that research is conducted according to international ethical and regulatory standards. These services will be provided across all three Projects and will support the activities in the other Cores. The Biostatistics & Clinical Research Core will be co-led by Dr. Ssenkusu (Biostastician and Lecturer, Makerere University College of Health Sciences – School of Public Health (MakCHS–SPH) and Dr. Hilsenbeck (Biostastician, Professor, Baylor College of Medicine (BCM), and Director of the Quantitative Sciences Shared Resource in the BCM Dan L. Duncan Comprehensive Cancer Center).

撒哈拉以南非洲儿童艾滋病毒/艾滋病及感染相关恶性肿瘤研究联盟 (PARCA)：生物统计学和临床​​研究核心（核心 C） 生物统计和临床研究核心（核心 C）的职责包括个人支持 项目和其他核心，以及整个联盟的整体数据管理。 为了实现这些目标，生物统计学和临床​​研究核心的目标是： 1. 数据管理：维护相关数据库，管理数据质量保证、数据安全 和备份，提供并促进信息检索和报告，监控所有进展 研究、更新硬件和软件、提供和改进文档。 2. 研究和实验设计：与所有项目和核心合作开展适当的研究 试点项目的设计、分析计划、样本量估计和可行性确定。 3. 统计分析：根据项目和核心产生的数据进行分析 目标 2 中生成的分析计划。 4. 质量保证和法规遵从：进行分析以确保产品的质量 通过生物样本的实验室和病理分析收集或生成的数据，以确保 研究是根据国际道德和监管标准进行的。 这些服务将在所有三个项目中提供，并将支持其他核心的活动。 生物统计学和临床​​研究核心将由 Ssenkusu 博士（麦克雷雷生物统计学家和讲师）共同领导 大学健康科学学院 - 公共卫生学院 (MakCHS-SPH) 和 Hilsenbeck 博士 （生物统计学家、贝勒医学院 (BCM) 教授、定量科学共享中心主任 BCM Dan L. Duncan 综合癌症中心的资源）。