Moffitt Postdoctoral Training Program in Molecular & Genetic Epidemiology

莫菲特分子博士后培训计划

• 批准号: 8076216
• 负责人: Kathleen M. Egan
• 金额: $ 46.83万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8076216
• 关键词: Area; Basic Science; Biological Monitoring; Biometry; Cancer Biology; Cancer Center; Cancer Control; Clinical; Clinical Oncology; Clinical Research; Data; Diagnosis; Discipline; Education; Educational Curriculum; Educational workshop; Ensure; Environment; Epidemiologic Studies; Epidemiology; Faculty; Fellowship Program; Florida; Future; Gene Expression Profiling; Individual; Interdisciplinary Study; K-Series Research Career Programs; Life Style; Malignant Neoplasms; Medicine; Methodology; Methods; Molecular; Molecular Epidemiology; Molecular Genetics; Monitor; Nanotechnology; Outcome; Postdoctoral Fellow; Proteomics; Qualifying; Recruitment Activity; Research; Research Design; Research Institute; Research Personnel; Research Project Grants; Research Training; Resources; Risk; Risk Assessment; Scientist; Screening for cancer; Screening procedure; Surveys; Technology; Training; Training Programs; Vision; Work; Writing; base; cancer care; cancer prevention; cancer risk; career; career development; design; experience; genetic epidemiology; genome wide association study; medical specialties; multidisciplinary; oncology; post-doctoral training; programs; success

DESCRIPTION (provided by applicant): We propose to develop, implement and evaluate a new education and career development program at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. The program will provide a specialized curriculum to prepare future academic researchers to integrate the latest technologies and full spectrum of outcomes (from risk to survival) in observational molecular and genetic epidemiology. Two postdoctoral fellows per year with advanced degrees in epidemiology, biostatistics, medicine or a related discipline will be recruited for a 2-3 year training program within this specialty area in cancer prevention and control that continues to see a shortage of qualified investigators. Fellows will participate in a multidisciplinary training experience that includes a core curriculum in molecular epidemiology, clinical oncology, cancer biology, plus special workshops in applied methodologies. Seminars developed for this training will include a survey of applications involving high-throughput advanced technologies and methods such as proteomics, genome-wide association studies, nanotechnology, gene expression profiling, and mathematical oncology that are leading the way to advances in screening, risk assessment, biomonitoring, and individual-based diagnosis and treatment, i.e. personalized medicine. In addition to the specialized curriculum in molecular epidemiology, a tailored program will be developed for each trainee that combines formal course work and hands-on experience in molecular, basic and clinical research under the guidance of at least two established investigators from different disciplines. In addition to a wide array of large, well-designed molecular and genetic epidemiologic studies, a unique asset for training at Moffitt is the availability of lifestyle, clinical and outcome data and biospecimens collected on many thousands of screening and cancer patients as part of Moffitt's Total Cancer Care research program. These resources afford an opportunity for trainees to apply study design and technology advances in personalized cancer care research. Each fellow will be required to define a research topic in the area of molecular or genetic epidemiology and write and defend a real or mock research grant or career development award application. Ongoing monitoring and over sight of the program by a dedicated faculty, and internal and external advisory boards, will ensure success in recruiting qualified candidates from multiple disciplines and backgrounds, and a training experience that prepares cancer researchers for careers in a rapidly changing, highly technical, interdisciplinary research environment.

描述（由申请人提供）：我们提议在佛罗里达州坦帕市的 H. Lee Moffitt 癌症中心和研究所制定、实施和评估一项新的教育和职业发展计划。该计划将提供专门的课程，帮助未来的学术研究人员在观察分子和遗传流行病学中整合最新技术和全方位的结果（从风险到生存）。每年将招募两名拥有流行病学、生物统计学、医学或相关学科高级学位的博士后研究员，在癌症预防和控制这一专业领域进行为期 2-3 年的培训计划，而该领域仍然缺乏合格的研究人员。研究员将参加多学科培训，包括分子流行病学、临床肿瘤学、癌症生物学的核心课程，以及应用方法学的特别研讨会。为本次培训开发的研讨会将包括对涉及高通量先进技术和方法的应用的调查，例如蛋白质组学、全基因组关联研究、纳米技术、基因表达谱和数学肿瘤学，这些技术和方法正在引领筛查、风险评估方面的进步、生物监测和个体化诊断和治疗，即个体化医疗。除了分子流行病学的专业课程外，还将在至少两名来自不同学科的知名研究人员的指导下，为每位学员开发一个量身定制的课程，结合正式的课程作业和分子、基础和临床研究的实践经验。除了一系列精心设计的大型分子和遗传流行病学研究之外，莫菲特培训的一项独特资产是，作为莫菲特培训的一部分，可以获得从数千名筛查和癌症患者身上收集的生活方式、临床和结果数据以及生物样本。全面癌症护理研究计划。这些资源为学员提供了在个性化癌症护理研究中应用研究设计和技术进步的机会。每位研究员都需要在分子或遗传流行病学领域定义一个研究主题，并撰写和辩护真实或模拟的研究资助或职业发展奖申请。由专门的教员以及内部和外部咨询委员会对该项目进行持续监控和监督，将确保成功招募来自多个学科和背景的合格候选人，并确保癌症研究人员为快速变化、高技术性的职业做好准备的培训经验，跨学科的研究环境。