Moffitt Postdoctoral Training Program in Molecular & Genetic Epidemiology

莫菲特分子博士后培训计划

• 批准号: 8490701
• 负责人: Kathleen M. Egan
• 金额: $ 45.15万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8490701
• 关键词: Area; Basic Science; Biochemical; Biological Monitoring; Biometry; Biotechnology; Cancer Biology; Cancer Center; Cancer Control; Clinical; Clinical Oncology; Clinical Research; Data; Development; Diagnosis; Discipline; Education; Educational Curriculum; Educational workshop; Engineering; Ensure; Environment; Environmental Risk Factor; Epidemiologic Studies; Epidemiology; Etiology; Faculty; Family; Fellowship Program; Florida; Future; Gene Expression Profiling; Genetic Risk; Human Genetics; Individual; Interdisciplinary Study; K-Series Research Career Programs; Knowledge; Life Style; Malignant Neoplasms; Medicine; Mentors; Methodology; Methods; Molecular; Molecular Epidemiology; Molecular Genetics; Monitor; Nanotechnology; Outcome; Population; Postdoctoral Fellow; Prognostic Marker; Proteomics; Qualifying; Recruitment Activity; Research; Research Design; Research Institute; Research Personnel; Research Project Grants; Research Training; Resources; Risk; Risk Assessment; Science; Scientist; Screening for cancer; Surveys; Technology; Testing; Training; Training Programs; Vision; War; Work; Writing; base; cancer care; cancer prevention; cancer risk; career; career development; design; disorder prevention; experience; genetic epidemiology; genome wide association study; interest; medical specialties; multidisciplinary; novel; oncology; post-doctoral training; programs; screening; skills; success; tool

ABSTRACT We propose to develop, implement and evaluate a new education and career development program at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. The program will provide a specialized curriculum to prepare future academic researchers to integrate the latest technologies and full spectrum of outcomes (from risk to survival) in observational molecular and genetic epidemiology. Two postdoctoral fellows per year with advanced degrees in epidemiology, biostatistics, medicine or a related discipline will be recruited for a 2-3 year training program within this specialty area in cancer prevention and control that continues to see a shortage of qualified investigators. Fellows will participate in a multidisciplinary training experience that includes a core curriculum in molecular epidemiology, clinical oncology, cancer biology, plus special workshops in applied methodologies. Seminars developed for this training will include a survey of applications involving high-throughput advanced technologies and methods such as proteomics, genome-wide association studies, nanotechnology, gene expression profiling, and mathematical oncology that are leading the way to advances in screening, risk assessment, biomonitoring, and individual-based diagnosis and treatment, i.e. personalized medicine. In addition to the specialized curriculum in molecular epidemiology, a tailored program will be developed for each trainee that combines formal course work and hands-on experience in molecular, basic and clinical research under the guidance of at least two established investigators from different disciplines. In addition to a wide array of large, well-designed molecular and genetic epidemiologic studies, a unique asset for training at Moffitt is the availability of lifestyle, clinical and outcome data and biospecimens collected on many thousands of screening and cancer patients as part of Moffitt's Total Cancer Care research program. These resources afford an opportunity for trainees to apply study design and technology advances in personalized cancer care research. Each fellow will be required to define a research topic in the area of molecular or genetic epidemiology and write and defend a real or mock research grant or career development award application. Ongoing monitoring and over sight of the program by a dedicated faculty, and internal and external advisory boards, will ensure success in recruiting qualified candidates from multiple disciplines and backgrounds, and a training experience that prepares cancer researchers for careers in a rapidly changing, highly technical, interdisciplinary research environment.

抽象的 我们建议在佛罗里达州坦帕市的H. Lee Moffitt癌症中心和研究所开发，实施和评估一项新的教育和职业发展计划。该计划将提供一项专业的课程，以准备未来的学术研究人员，以整合观察性分子和遗传流行病学的最新技术和完整结果（从风险到生存）。每年有两个具有流行病学，生物统计学，药物或相关学科的高级学位的博士后研究员将在癌症预防和控制方面的专业领域进行2 - 3年的培训计划，这些计划将继续看到合格的调查人员的短缺。研究员将参加多学科培训经验，其中包括分子流行病学，临床肿瘤学，癌症生物学以及应用方法论的特殊研讨会的核心课程。为此培训开发的研讨会将包括对涉及高通量高级技术的应用调查以及诸如蛋白质组学，全基因组关联研究，纳米技术，基因表达概况和数学肿瘤学的方法，这些研究正在促进筛查，风险评估的进步， ，生物监测和基于个体的诊断和治疗，即个性化医学。除了分子流行病学的专业课程外，还将为每个受训者制定一个量身定制的计划，该计划将正式的课程工作和分子，基础和临床研究中的动手经验结合在不同学科的至少两名既定研究者的指导下。除了广泛的大型，精心设计的分子和遗传流行病学研究外，在莫菲特进行培训的独特资产是生活方式，临床和结果数据的可用性，以及在莫菲特（Moffitt）的一部分中收集的成千上万次筛查和癌症患者的生物测量总癌症护理研究计划。这些资源为受训者提供了在个性化癌症护理研究中应用研究设计和技术进步的机会。每个研究员都需要在分子或遗传流行病学领域定义一个研究主题，并撰写并捍卫真正或模拟的研究赠款或职业发展奖应用程序。敬业的教职员工以及内部和外部咨询委员会正在进行的监视和整个计划，将确保成功地从多个学科和背景招募合格的候选人，以及为癌症研究人员做好准备，以使癌症研究人员在快速变化的高度技术上为职业做好准备，跨学科研究环境。