Multi-spectral Imaging of Cadaveric Organ Viability during Organ Resuscitation

器官复苏期间尸体器官活力的多光谱成像

• 批准号: 7967887
• 负责人: Alexander Gorbach
• 金额: $ 1.6万
• 依托单位: NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7967887
• 关键词: Anterior; Devices; Evaluation; Family suidae; Hour; Image; Individual; Intervention; Ischemia; Kidney; Measurement; Measures; Methods; Monitor; Organ; Organ Viability; Performance; Perfusion; Pulsatile Flow; Pump; Resistance; Resuscitation; Solutions; Surface; Temperature; Time; improved; pressure

IR imaging was used to monitor porcine kidneys. Kidneys were placed on a hypothermic PP machine for 14 hours. Each kidney was cannulated and placed on an individual cassette primed with Belzer Machine Perfusion Solution, while perfusate temperature (T degrees C), pressure, V, and R were recorded for each kidney. An IR camera was focused on the anterior surface of each kidney. This device is sensitive to 0.02 degree C change at 3-5 micron wavelengths. Images were collected every 5 sec. The degree of perfusion homogeneity was assessed. IR assessment of temperature correlates negatively with gross flow and positively with gross intrarenal resistance. Additionally, IR evaluation revealed inhomogeneous perfusion that improved over time with PP and was not evident by standard measurements of flow and resistance.

红外成像用于监测猪肾脏。 将肾脏放在低温PP机器上14小时。 每个肾脏被插管，并将其放置在带有Belzer Machine灌注溶液的单独盒式上，而灌注液温度（T度C），压力，V和R为每个肾脏记录。 IR摄像头专注于每个肾脏的前表面。 该设备对3-5微米波长的0.02度更换敏感。 每5秒收集一次图像。 评估了灌注均匀性的程度。 IR的温度评估与总流量和正面耐药性正相关。此外，IR评估表明，随着时间的流逝，随着时间的流逝，不均匀的灌注会改善，并且由于流动和电阻的标准测量而言并不明显。