MUSHROOM

蘑菇

• 批准号: 7951351
• 负责人: PENNY M KRIS-ETHERTON
• 金额: $ 0.83万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951351
• 关键词: Agaricales; Antioxidants; Biological Availability; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Ergothioneine; Food; Funding; Goals; Grant; Health Benefit; Human; Inflammation; Institution; Research; Research Personnel; Resources; Source; United States National Institutes of Health; functional food; nutrition

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The growing demand of functional foods has sparked research on identifying bioactive components in food. Current research has demonstrated that many of the functional components found in food confer health benefits beyond basic nutrition. Mushrooms contain ergothioneine (ET), a known potent antioxidant. ET was discovered in 1909 and although it has been widely studied, its bioavailability in humans is still not clear. The goal of this project is to assess the bioavailability of ET from mushrooms and evaluate its bioactive effect on antioxidant capacity and inflammation.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 对功能性食品不断增长的需求引发了对食品中生物活性成分的研究。目前的研究表明，食品中的许多功能成分所带来的健康益处超出了基本营养的范围。蘑菇含有麦角硫因 (ET)，一种已知的有效抗氧化剂。 ET于1909年被发现，尽管已被广泛研究，但其在人体中的生物利用度仍不清楚。该项目的目标是评估蘑菇中 ET 的生物利用度，并评估其对抗氧化能力和炎症的生物活性作用。