COBRE: UD: ADMININSTRATION CORE: OSTEOARTHRITIS: PREVENTION AND TREATMENT

COBRE：UD：管理核心：骨关节炎：预防和治疗

• 批准号: 7720202
• 负责人: Thomas S Buchanan
• 金额: $ 79.07万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7720202
• 关键词: Address; Area; Arthritis; Basic Science; Biomechanics; Biomedical Engineering; Centers of Research Excellence; Clinic; Clinical; Clinical Treatment; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Degenerative polyarthritis; Delaware; Engineering; Faculty; Foundations; Funding; Goals; Grant; Institution; Intervention; Lead; Mechanics; Mentors; Physical therapy; Prevention; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Science; Source; Tissues; Training; United States National Institutes of Health; Universities; Woman; Work; base; bioimaging; college; instrumentation; member; multidisciplinary; tool; translational medicine; trend

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In this COBRE II grant we aim to develop multidisciplinary researchers in the field of osteoarthritis (OA), from the lab bench to the clinic, with a unique focus on mentoring Women In Science and Engineering (WISE). In this proposal, each of the five projects is lead by a women faculty member. Women faculty in science, and especially engineering, are under-represented. At the University of Delaware, women make up 17% of the faculty of science and 10% of the faculty in engineering. Delaware is not unique in this regard. National averages show similar trends (Nelson, 2005). Thus, our aim is to provide a forum for mentoring and promoting women faculty working in the field of arthritis research. This COBRE II grant, as is COBRE I grant, is administered through our Center for Biomedical Engineering Research (CBER) at the University of Delaware. CBER has been in existence since the early 1990's and provides a forum for researchers in different departments to work together on mulitidisciplinary projects related to translational medicine using biomedical engineering tools. Without exception, all of the research grants through the center (which are mostly R01s) have faculty from at least two colleges working together on multidisciplinary projects that tie together both basic research and clinical treatment. The scientific goal of this COBRE II grant is to create the infrastructure and expertise base to address the mechanisms of OA, as well as its prevention and treatment. The uniqueness of the approach to be employed by our center will be the examination of OA from the integrated perspectives of tissue mechanics, biomechanics, physical therapy and clinical intervention. A foundation for this has been laid by our initial COBRE I grant. In our proposed work, we will build upon the distinctive organization of CBER and the collaborative projects described in this application. In addition to the integration provided by the overarching research aims of the Center, as mentioned above, we aim to establish a core facility for mentoring women in science and engineering. We also aim to continue and expand our instrumentation core in the area of biomedical imaging. Multiple projects benefit from the core facilities provided by the Center. We also encourage other faculty at the University that are not directly involved in the Center to make use of these cores, and will provide mentoring, technical staff and training to make such benefits more accessible.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在这笔鞋带II赠款中，我们旨在从实验室长凳到诊所开发骨关节炎（OA）领域的多学科研究人员，其独特的重点是指导科学和工程领域的女性（WISE）。在此提案中，五个项目中的每个项目都是由女教师领导的。科学妇女教职员工，尤其是工程学的人数不足。在特拉华大学，妇女占科学学院的17％和工程学院的10％。在这方面，特拉华州并不是独一无二的。国家平均值显示出类似的趋势（Nelson，2005年）。因此，我们的目的是提供一个论坛，以指导和促进关节炎研究领域的女教师。 这项Cobre II赠款和Cobre I Grant也是通过我们在特拉华大学的生物医学工程研究中心（CBER）管理的。自1990年代初以来，CBER就一直存在，并为不同部门的研究人员提供了一个论坛，以使用生物医学工程工具共同研究与转化医学有关的穆利蒂学科项目。毫无例外的是，通过中心（主要是R01）的所有研究赠款都有来自至少两所从事多学科项目的大学的教职员工，这些大学将基础研究和临床治疗既将其融合在一起。 这项圆顶II赠款的科学目标是创建基础设施和专业知识基础，以解决OA的机制及其预防和治疗。我们中心要采用的方法的独特性将是从组织力学，生物力学，物理治疗和临床干预的综合观察OA检查。我们的最初的毛托赠款为此奠定了基础。在我们提出的工作中，我们将建立在CBER的独特组织以及本应用程序中描述的协作项目的基础上。 除了上述中心的总体研究目标所提供的整合外，我们旨在为指导妇女在科学和工程领域建立核心设施。我们还旨在继续在生物医学成像领域继续我们的仪器核心。多个项目受益于中心提供的核心设施。我们还鼓励大学的其他教师不直接参与中心来利用这些核心，并将提供指导，技术人员和培训，以使这些好处更容易获得。