Pathology Core

病理学核心

• 批准号: 7686486
• 负责人: JACQUELINE Jones COALSON
• 金额: $ 12.9万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7686486
• 关键词: Autopsy; Biochemical; Biopsy; Collagen; Data; Databases; Elastin; Electrons; Evaluation; Goals; Histocytochemistry; Individual; Laboratories; Lesion; Lung; Microscopic; Pathology; Preparation; Procedures; Research; Research Personnel; Services; Slide; Specimen; Tissues; immunocytochemistry; light microscopy; research study; tissue processing

The Pathology Core will provide the needed necropsy and slide preparation services for all the projects in the application. Lung pathology interpretation, grading of lesions using appropriate quantitaive analyses and maintaining a database of the pathological findings are planned. Immunochemical and histochemical preparations of designated lungs will be done and analysed to further clarify and expand potential pathogenetic features of the lesions. Whole lung collagen and elastin determinations willl be done in order to correlate biochemical findings with the histopathological findings. These data will augment and facilitate the research goals outlined in the four projects.

病理核心将为所有项目提供所需的尸检和幻灯片准备服务 应用程序。 Lung pathology interpretation, grading of lesions using appropriate quantitaive analyses and 计划维护病理发现的数据库。免疫化学和组织化学 将进行指定肺的准备，并进行分析，以进一步澄清和扩大潜力 病变的致病特征。将完成整个肺胶原蛋白和弹性蛋白测定 将生化发现与组织病理学发现相关。这些数据将增加并促进 四个项目中概述的研究目标。