COBRE: CORE A: ADMIN CORE; EXPANDING U OF ALASKAS HEALTH RESEARCH CAPABILITY

COBRE：核心 A：管理核心；

• 批准号: 7381220
• 负责人: Gerald Mohatt
• 金额: $ 4.62万
• 依托单位: UNIVERSITY OF ALASKA FAIRBANKS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381220
• 关键词: COBRE; CORE; ADMIN; EXPANDING; ALASKAS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This COBRE grant to establish the Center for Alaska Native Health Research is based upon a community-based participatory research paradigm that fosters basic and applied research. The overall goal is to facilitate the development of a sustainable, NIH-funded research center specifically focused on identifying the cultural-behavioral, nutritional, and genetic risk/protective factors associated with increased weight, type two diabetes, and cardiovascular disease among Alaska Natives. The Administrative core provides infrastructure to support this research among remote rural Alaska Native communities. Accomplishments of the Administrative core for year five include: A. Received approval from three new villages to gather data. All of these villages have significant relationships historically to those villages already sampled; therefore, many individuals are related to current participants. This will increase the power of our sample for genetic analyses. B. Identified five prospective investigators for the competitive renewal whose proposals have been approved by the EAC and identified the core structures to support these projects. Received support from the villages for the renewal indicating their willingness to participate in continued research. Planned the renewal with our community partners after presenting results of the first round of data gathering. C. We have secured the continued support of the University for the space and positions needed for the renewal, which will allow us to build a long-term biomedical research program. The university has made biomedical research one of its top funding priorities when new state research dollars become available. D. Infrastructure has grown to over 60 full- and part-time investigators and support staff. This capacity has allowed us to enroll 907 Yup¿ik participants in the study. It has stimulated submissions of one R01, one R24, two R21s, one R03, and one R34. Four R-series grants were received by CANHR investigators. E. Productivity of CANHR investigators has significantly increased since data analysis has progressed adequately. They have presented 60 abstracts at national and regional conferences, have 20 articles or books in press, had 21 articles or book chapters published, and currently have 12 articles submitted for review.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构是针对该中心的，这不是调查人员的机构。这项旨在建立阿拉斯加本地健康研究中心的毛线赠款基于培养基础研究和应用研究的基于社区的参与研究范例。总体目标是支持发展一个可持续的，NIH资助的研究中心，专门针对识别与体重增加，第二型糖尿病和心血管疾病相关的文化行为，营养和遗传风险/保护因素。行政核心提供了基础架构，以支持阿拉斯加遥远的阿拉斯加本土社区中的这项研究。第五年的行政核心成就包括：A。获得了三个新村庄的批准来收集数据。所有这些村庄在历史上与已经采样的村庄都有很大的关系。因此，许多人与当前参与者有关。这将增加我们样本的遗传分析的力量。 B.确定了五名竞争性更新的潜在调查人员，其提案已获得EAC的批准，并确定了支持这些项目的核心结构。获得了村庄的支持，以表明他们愿意参加继续研究。在提出第一轮数据收集的结果后，计划与我们的社区合作伙伴进行续签。 C.我们已经确保了大学对续订所需的空间和职位的持续支持，这将使我们能够建立长期的生物医学研究计划。当新的州研究资金可用时，该大学将生物医学研究成为其最重要的资金优先事项之一。 D.基础设施已成长为60多名全日制和兼职调查人员和支持人员。这种能力使我们能够将907 YUP授予IK参与者参加该研究。它刺激了一个R01，一个R24，两个R21，一个R03和一个R34的提交。 CANHR调查人员收到了四个R系列赠款。 E. CANHR研究者的生产率已显着提高，因为数据分析已得到充分进展。他们在国家和地区会议上介绍了60篇摘要，在新闻界有20篇文章或书籍，有21篇文章或书籍章节，目前已提交12篇文章供审查。