CCTG 560A: VIRAL POPULATION KINETICS

CCTG 560A：病毒群体动力学

• 批准号: 7374181
• 负责人: SUSAN E LITTLE
• 金额: $ 3.39万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7374181
• 关键词: RNA; lymph; lymphocyte; plasma; tissues

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluate the rates of HIV production and clearance after initiating or discontinuing antiretroviral treatment. Evaluate the dynamics of different virus populations (according to resistance pattern or host cell) after initiating or discontinuing antiretroviral treatment. Evaluate viral populations in lymph tissue in subjects with and without detectable HIV RNA in the plasma, and evaluate viral populations in lymphocytes when HIV RNA levels are undetectable in the plasma.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。启动或中断抗逆转录病毒治疗后，评估HIV产生和清除率的速率。在开始或停止抗逆转录病毒治疗后，评估不同病毒群体（根据抗性模式或宿主细胞）的动力学。评估血浆中有或没有可检测的HIV RNA受试者的淋巴组织中的病毒群体，并在血浆中无法检测到HIV RNA水平时评估淋巴细胞中的病毒群体。