COGNITIVE FUNCTION IN THE AGED MONKEY

老年猴子的认知功能

• 批准号: 7349639
• 负责人: PETER R RAPP
• 金额: $ 17.15万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7349639
• 关键词: COGNITIVE; FUNCTION; AGED; MONKEY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall aims of the project are to define the effects of normal, non-pathological aging on the component processes of memory, and to evaluate these changes in relation to markers of ovarian hormone impairment in rhesus monkeys. Groups of young and aged subjects are tested across a battery of well-studied, standardized neuropsychological task as well as newly developed procedures designed to provide a sensitive window on cognitive aging. Urinary hormone profiles are determined for all female monkeys periodically throughout the project in order to relate these parameters to individual differences in the status of age-related memory decline.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。该项目的总体目的是定义正常，非病理衰老对记忆组件过程的影响，并评估与恒河猴卵巢激素障碍标志物相关的这些变化。在一系列精心研究，标准化的神经心理学任务以及旨在提供有关认知衰老敏感窗口的新开发程序中，对年轻和老年受试者组进行了测试。在整个项目中定期确定所有雌性猴子的尿激素谱，以将这些参数与年龄相关记忆下降状态的个体差异联系起来。