OLFACTORY CONDITIONING OF FLAVORS IN MACACA NEMESTRINA

猕猴桃风味的嗅觉调节

• 批准号: 7349321
• 负责人: GENE P. SACKETT
• 金额: $ 13.2万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7349321
• 关键词: OLFACTORY; CONDITIONING; FLAVORS; MACACA; NEMESTRINA; OLFACTORY; CONDITIONING; FLAVORS; MACACA; NEMESTRINA

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Olfactory conditioning in human infants can enhance ingestion of new and aversive solutions, thereby aiding medicine consumption and diet transitions. Olfactory conditioning is also useful for studying long term memory. Preliminary to a study of olfactory conditioning, we assessed scent preference/aversion in 5 nursery raised infants ranging in age from 5-10 months. The method uses 10-cm diameter circles with a .5-in center hole, cut from coffee filters, soaked for 60-sec in pure extracts of lemon, almond, or vanilla. Two bottles containing 500 ml of water are attached to the left and right rear cage wall, at lixit height (turned off) 1-ft from the cage floor. The circles were randomly placed on the bottles, 2-in from the spout end, from 11:00-14:45 hours on each of 21 test days. Baseline sessions used unscented bottles. Test sessions paired each scent against water, as well as each against the other two scents. Amount of water consumed from each bottle was recorded. Infants consumed more water paired with almond and vanilla than at baseline, demonstrating that these scents enhanced ingestion. Water paired with lemon was at or below baseline, suggesting a relative aversion to this scent. We conclude that some scents can enhance the intake of water by infant macaques. However, when animals were tested for retention 2-6 months after initial conditioning only 4 of 10 preferred the conditioned flavor.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。人类婴儿中的嗅觉调节可以增强对新的和厌恶溶液的摄入，从而有助于医学消费和饮食过渡。嗅觉调节也可用于研究长期记忆。对于一项嗅觉调节研究的初步，我们评估了5-10个月的5个幼儿园的气味偏好/厌恶。该方法使用带有.5英寸中心孔的10厘米直径圆圈，从咖啡过滤器中切出，浸泡在柠檬，杏仁或香草的纯提取物中60秒。两个瓶子含有500毫升水的瓶子在左侧和右后笼壁上，距离lixit高度（关闭）距离笼子地板1英尺（关闭）。圆圈随机放在瓶子上，距离喷口端2英寸，在21个测试天中的每一个11：00-14：45小时。基线会话使用无知的瓶子。测试课程将每种气味与水以及其他两种气味配对。记录了从每个瓶子中消耗的水量。婴儿与杏仁和香草搭配的水多于基线，这表明这些气味增强了摄入量。与柠檬配对的水在基线或低于基线，表明对这种气味有相对的厌恶。我们得出的结论是，某些气味可以通过婴儿猕猴增强水的摄入量。但是，当动物在初次调节后2-6个月进行测试时，只有10个只有10个选择条件风味。