Parent Alcoholism Among ADHD Youth: A Longitudinal Study

多动症青少年的父母酗酒：一项纵向研究

• 批准号: 7058855
• 负责人: Michael P Marshal
• 金额: $ 9.57万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7058855
• 关键词: alcoholism /alcohol abuse; attention deficit disorder; behavior prediction; behavioral /social science research tag; clinical research; disease /disorder proneness /risk; human data; longitudinal human study; mental health epidemiology; parent offspring interaction; substance abuse epidemiology; young adult human (21-34)

DESCRIPTION (provided by applicant): This K01 award will provide specialized training in the skills necessary to conduct longitudinal research and to identify risk and protective factors in the development of alcohol use disorders in high-risk youth populations. The training plan will include an intensive study of alcohol use disorders (AUDs), longitudinal research and quantitative methods, and Attention-Deficit/Hyperactivity Disorder (ADHD), which will be accomplished via four primary training mechanisms: 1) guided readings in each content area designed by mentors and consultants; 2) regular meetings with each consultant to discuss professional development, grantsmanship, training/career goals, and ongoing data analysis and manuscripts; and 3) a series of workshops and courses led by leading experts in the field and designed to address the training goals. The training plan will also be facilitated by a series of complimentary research aims, which will include a systematic evaluation of the concurrent, longitudinal, and bidirectional relationships between two central risk factors for the development of alcohol use disorders (AUDs): parent alcoholism and childhood ADHD. Moreover the proposed study will evaluate the role of offspring ADHD and family functioning in the intergenerational transmission of AUDs. These aims will be examined using an original data collection project designed to examine the role of family functioning in ADHD families with alcoholic parents, and data from two ongoing longitudinal studies: the Pittsburgh ADHD Longitudinal Study (PALS) conducted by Drs. Brooke Molina (AA11873) and William Pelham (DA12414), and the Berkeley study of preadolescent ADHD girls, conducted by Dr. Hinshaw (MH45064). Both of these studies are the largest of their kind, and include comprehensive, state-of-the-art assessment batteries administered in face-to-face interviews with the target and at least one custodial parent. Moreover, they both include extensive longitudinal follow-up assessments in adolescence and young adulthood. The results of the proposed research and the skills obtained via the proposed training plan will serve as a springboard for future R01 studies that will examine the role of parent and offspring psychopathology in family functioning and the intergenerational transmission of AUDs, with the ultimate purpose of identifying targets for AUD prevention and intervention programs.

描述（由申请人提供）：该 K01 奖项将提供进行纵向研究所需技能的专门培训，并确定高危青年人群中酒精使用障碍发展的风险和保护因素。培训计划将包括对酒精使用障碍（AUD）、纵向研究和定量方法以及注意力缺陷/多动障碍（ADHD）的深入研究，这将通过四种主要培训机制来完成：1）每个内容的引导阅读由导师和顾问设计的区域； 2) 与每位顾问定期举行会议，讨论专业发展、资助、培训/职业目标以及正在进行的数据分析和手稿； 3) 由该领域领先专家主持的一系列研讨会和课程，旨在实现培训目标。该培训计划还将通过一系列补充研究目标来促进，其中包括对酒精使用障碍（AUD）发展的两个主要危险因素（父母酗酒和儿童）之间的并发、纵向和双向关系进行系统评估多动症。此外，拟议的研究将评估后代 ADHD 和家庭功能在 AUD 代际传播中的作用。这些目标将使用一个原始数据收集项目来检验，该项目旨在检查父母酗酒的 ADHD 家庭中家庭功能的作用，以及来自两项正在进行的纵向研究的数据：匹兹堡 ADHD 纵向研究 (PALS)，由 Drs. 进行。 Brooke Molina (AA11873) 和 William Pelham (DA12414)，以及由 Hinshaw 博士 (MH45064) 进行的伯克利青春期前多动症女孩研究。这两项研究都是同类研究中规模最大的，并且包括通过与目标和至少一名监护父母进行面对面访谈而进行的全面、最先进的评估。此外，它们都包括对青春期和成年早期的广泛纵向随访评估。拟议研究的结果以及通过拟议培训计划获得的技能将作为未来 R01 研究的跳板，该研究将研究父母和后代精神病理学在家庭功能和 AUD 代际传播中的作用，最终目的是确定AUD 预防和干预计划的目标。