Identifying Mediated Pathways of Risk for Substance Use in Sexual Minority Girls

确定性少数女孩药物使用风险的介导途径

• 批准号: 8731844
• 负责人: Michael P Marshal
• 金额: $ 22.83万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8731844
• 关键词: Adolescence; Adolescent; Adopted; Adult; Affect; Age; Alcohol or Other Drugs use; Bisexual; Build-it; Centers for Disease Control and Prevention (U.S.); Childhood; Communities; Conflict (Psychology); Consensus; Data; Data Set; Depression and Suicide; Development; Foundations; Future; Gays; Goals; Grant; Growth; Health; Heterosexuals; Institute of Medicine (U.S.); Intervention Studies; Lesbian; Link; Literature; Longevity; Longitudinal Studies; Marshal; Mediating; Mediator of activation protein; Mental Health; Meta-Analysis; Minority; Modeling; Parental Consent; Parenting Education; Pathway interactions; Pharmaceutical Preparations; Preparation; Prevention program; Preventive Intervention; Process; Public Health; Publishing; Race; Reporting; Research; Research Personnel; Risk; Sampling; Schools; Sex Orientation; Single Parent; Stress; Subgroup; Substance abuse problem; Suicide; Teenagers; Testing; Time; Writing; Youth; adolescent substance use; base; binge drinking; boys; comparison group; conduct problem; design; expectation; girls; health disparity; heuristics; high risk; high risk sexual behavior; innovation; intervention program; novel; parallel processing; psychosocial; public health relevance; response; sex; sexual minority; social; theories; young adult

DESCRIPTION (provided by applicant): The central goals of this competing renewal grant are to: (1) identify specific mediated pathways of risk for substance use and abuse among sexual minority girls (SMGs; girls who report same-sex sexual orientation) and (2) identify developmentally appropriate protective factors that can inform the development of novel prevention and intervention studies tailored for this high risk group. SMGs are 400% more likely to report substance use than are heterosexual girls. Recent results from grant years 1-3 showed that SMGs reported multiple mental health disparities including risky sexual behavior that were significant across all levels of all demographic covariates. SMG substance use disparities seen in adolescence increased as girls transition to young adulthood and change in binge drinking over time is more closely linked to suicidality in SMGs than it is in boys. In grant years 1-3 we were highly successful in documenting the persistence of SMG substance use disparities and identifying important psychosocial correlates of the disparities. Building on this foundation, we propose a heuristic model that articulates the most probable (empirically-supported, theory-driven) pathways of risk for substance use in SMGs. Dozens of conceptual models have been developed to describe risk for substance use among other at-risk teens; however no one has developed an empirically supported heuristic model that describes risk pathways for sexual minority youth. Preliminary data from grant years 1-3 and our proposed data sets (Add Health and the Pittsburgh Girls Study) show strong preliminary support for our hypothesized mediate pathways (stress-negative affect, social marginalization, and future expectations pathways). This proposal will build upon this foundation, and seeks to move the field forward by proposing and testing several longitudinal mediated pathways of risk and identify modifiable protective factors that will inform the design of a novel prevention and intervention program for SMGs.

说明（由申请人提供）：这项竞争性更新赠款的核心目标是：(1) 确定性少数女孩（SMG；报告同性性取向的女孩）物质使用和滥用风险的具体介导途径，以及（ 2）确定适合发育的保护因素，为针对这一高危人群量身定制的新型预防和干预研究的发展提供信息。 SMG 报告药物滥用的可能性比异性恋女孩高 400%。资助第 1-3 年的最新结果显示，SMG 报告了多种心理健康差异，包括危险性行为，这些差异在所有人口协变量的各个层面上都很显着。随着女孩过渡到成年早期，青少年时期的 SMG 物质使用差异会加大，而且随着时间的推移，SMG 中酗酒情况的变化与自杀倾向的关系比男孩更密切。在资助的第 1-3 年，我们非常成功地记录了 SMG 物质使用差异的持续存在，并确定了这些差异的重要社会心理相关性。在此基础上，我们提出了一个启发式模型，该模型阐明了 SMG 中物质使用最可能的（经验支持、理论驱动的）风险途径。已经开发了数十个概念模型来描述其他高危青少年的药物使用风险；然而，没有人开发出一种有经验支持的启发式模型来描述性少数青少年的风险路径。第 1-3 年资助的初步数据和我们提出的数据集（添加健康和匹兹堡女孩研究）显示出对我们假设的中介路径（压力负面影响、社会边缘化和未来期望路径）的强有力的初步支持。该提案将在此基础上建立，并寻求通过提出和测试几种纵向介导的风险途径来推动该领域向前发展，并确定可修改的保护因素，这些因素将为 SMG 的新型预防和干预计划的设计提供信息。