Substance Use Disparities Among Sexual Minority Girls: A Longitudinal Study

性少数女孩的药物使用差异：一项纵向研究

• 批准号: 8145272
• 负责人: Michael P Marshal
• 金额: $ 22.04万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8145272
• 关键词: 8 year old; Address; Adolescence; Adolescent; Adult; African American; Age; Age of Onset; Alcohol or Other Drugs use; Alcohols; Behavior; Bisexual; Caucasians; Caucasoid Race; Cigarette; Communities; Cross-Sectional Studies; Data Analyses; Data Set; Development; Drug usage; Ethnic Origin; Frequencies; Future; Gays; Goals; Health; Health Personnel; Health Services; Heterosexuals; Illicit Drugs; Individual; Lesbian; Literature; Longitudinal Studies; Mediating; Mediator of activation protein; Mental Depression; Mental Health; Meta-Analysis; Minority; Monitor; National Institute of Drug Abuse; National Institute on Alcohol Abuse and Alcoholism; Outcome; Parent-Child Relations; Parental Consent; Pathway interactions; Pattern; Population; Prejudice; Preventive Intervention; Psychopathology; Psychosocial Factor; Public Health; Recruitment Activity; Reporting; Risk; Risk Factors; Risk Marker; Role; Sampling; Schools; Sex Behavior; Sex Orientation; Social support; Stress; Subgroup; Substance abuse problem; Theoretical model; Time; Victimization; Vulnerable Populations; Youth; adolescent substance use; age group; base; design; deviant; family structure; girls; health disparity; high risk; high risk sexual behavior; innovation; intervention program; longitudinal course; novel strategies; peer; peer victimization; prevent; psychosocial; public health relevance; research study; self esteem; sex; systematic review; theories; young adult

DESCRIPTION (provided by applicant): The central goal of this study is to describe and explain longitudinal patterns of adolescent substance use among sexual minority girls. Our meta-analysis of 18 cross-sectional studies showed that the odds of substance use for sexual minority girls were 400% higher than they were for heterosexual girls; However, few if any studies have examined longitudinal patterns of use, significant risk markers, mediators, or moderators of this disparity (Marshal et al., 2008). Only two studies to date have examined trajectories of substance use behavior among young sexual minority youth, and suggest that these disparities are maintained or increase over time as sexual minority youth approach young adulthood (Corliss et al., 2008; Marshal et al., 2009). Furthermore, cross-sectional evidence suggests that substance use among sexual minority girls is associated with other psychosocial health problems such as depression (Fergusson et al., 1999; Garofalo, et al., 1998). However no studies to date have examined the role of psychosocial risk factors in the long term patterns of substance use in this high risk population. We are proposing a developmental interpretation and application of Minority Stress Theory (MST; Hatzenbuehler, 2009; Meyer, 2003). Our new approach combines it with Developmental Psychopathology Theory (Cicchetti & Cohen, 2006) in order to articulate the unique needs and problems faced by sexual minority youth. Our Specific Aims are to: (1) Examine disparities between sexual minority girls and heterosexual girls in the age of onset and longitudinal course of substance use (quantity and frequency of cigarette, alcohol, and illicit drug use); (2) Determine whether the association between sexual minority status and trajectories of substance use is moderated or mediated by other psychosocial risk and protective factors (e.g., mental health, risky sexual behavior, deviant peer affiliation, victimization, social support, self-esteem, parent-child relationship quality); and (3) Explore whether the associations between sexual minority status, psychosocial factors, and substance use vary across demographic subgroups (e.g., age, ethnicity, family structure, SES). This proposal is innovative because: (1) it will be the first to characterize the onset, course, and long-term psychosocial correlates of substance use among sexual minority girls; (2) it will develop a new theoretical approach to describing and explaining risk for substance use among sexual minority youth; and we will (3) fill critical gaps in the health disparities and health services literatures, as well as provide important descriptive and explanatory information about longitudinal pathways of risk among this highly vulnerable group that will help inform future research, prevention, and intervention programs. PUBLIC HEALTH RELEVANCE: The primary goal of this study is to describe and explain longitudinal patterns of adolescent substance use among sexual minority girls. Recent meta-analysis results showed that the odds of adolescent substance use for sexual minority girls were 400% higher than they were for heterosexual girls. However, very few studies have examined longitudinal patterns of use, significant risk markers, mediators, or moderators of this disparity. This longitudinal study will characterize the onset, course, and long-term psychosocial risk and protective factors associated with substance use among sexual minority girls, and in doing so it will fill critical gaps in the health disparities and health services literatures.

描述（由申请人提供）：本研究的中心目标是描述和解释性少数女孩青少年物质使用的纵向模式。我们对 18 项横断面研究的荟萃分析表明，性少数女孩使用药物的几率比异性恋女孩高 400%；然而，很少有研究考察这种差异的纵向使用模式、显着风险标记、调节因素或调节因素（Marshal 等，2008）。迄今为止，只有两项研究考察了年轻性少数群体的物质使用行为轨迹，并表明，随着性少数群体青年接近成年，这些差异会随着时间的推移而维持或增加（Corliss 等人，2008 年；Marshal 等人，2009 年） ）。此外，横断面证据表明，性少数女孩的药物使用与抑郁等其他社会心理健康问题有关（Fergusson 等人，1999 年；Garofalo 等人，1998 年）。然而，迄今为止还没有研究探讨心理社会危险因素在这一高危人群的长期药物使用模式中的作用。我们提出对少数群体压力理论的发展解释和应用（MST；Hatzenbuehler，2009；Meyer，2003）。我们的新方法将其与发展精神病理学理论（Cicchetti & Cohen，2006）相结合，以阐明性少数青少年面临的独特需求和问题。我们的具体目标是： (1) 检查性少数女孩和异性恋女孩在物质使用的发病年龄和纵向过程（吸烟、酗酒和非法药物使用的数量和频率）方面的差异； (2) 确定性少数地位与物质使用轨迹之间的关联是否受到其他心理社会风险和保护因素的调节或调节（例如心理健康、危险性行为、异常同伴关系、受害、社会支持、自尊、亲子关系质量）； (3) 探讨不同人口亚组（例如年龄、种族、家庭结构、社会经济地位）之间的性少数地位、心理社会因素和物质使用之间的关联是否有所不同。该提案具有创新性，因为：（1）它将是第一个描述性少数女孩物质使用的发生、过程和长期社会心理相关性的特征； (2) 它将开发一种新的理论方法来描述和解释性少数青少年的药物使用风险；我们将（3）填补健康差异和卫生服务文献中的关键空白，并提供有关这一高度脆弱群体的纵向风险路径的重要描述性和解释性信息，这将有助于为未来的研究、预防和干预计划提供信息。 公共卫生相关性：本研究的主要目标是描述和解释性少数女孩青少年物质使用的纵向模式。最近的荟萃分析结果显示，性少数女孩青少年时期使用药物的几率比异性恋女孩高 400%。然而，很少有研究考察这种差异的纵向使用模式、显着风险标记、中介因素或调节因素。这项纵向研究将描述性少数女孩中与药物使用相关的发病、病程和长期心理社会风险和保护因素，从而填补健康差异和卫生服务文献中的关键空白。