Biostatstics

生物统计学

基本信息

批准号：
7270274
负责人：
DONALD A BERRY
金额：
$ 13.73万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-04-01 至 2012-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7270274
关键词：
Advocate Age Animals Apache Indians Apple Area Basic Science Berry Bioinformatics Bioinformatics Shared Resource Biological Biological Markers Biomedical Research Biometry Biostatistics Core Books Breast Cancer Prevention Budgets Calendar Cancer Center Cancer Center Support Grant Caring Categories Cell Line Cells Chairperson Chemical Agents Cities Client Clinical Clinical Investigator Clinical Trials Clinical Trials Design Collaborations Complex Computers Conduct Clinical Trials Confidential Information Consult Consultations Dana-Farber Cancer Institute Data Data Analyses Data Collection Databases Direct Costs Directories Doctor of Medicine Doctor of Philosophy Drug Formulations Drug Industry Electronic Mail Electronics Ensure Equipment Evaluation Experimental Designs Face Facilities and Administrative Costs Faculty Floor Funding Future Gene Expression Genetic Goals Health Health Services Research High Performance Computing Hospitals Housing Human Resources In Vitro Individual Instruction Internet Intranet Laboratories Laboratory Research Language Last Name Libraries Linux Location Mails Manuscripts Mathematical Biology Mathematics Medical Faculty Medical Oncology Medical Research Memory Methods Michigan Mission Modeling Molecular Molecular Biology Monitor Mus Names National Cancer Institute None or Not Applicable Numbers Outpatients Patient Care Patients Personal Satisfaction Pharmaceutical Preparations Phase Principal Investigator Printing Procedures Production Protein Array Proteomics Public Health Publications Published Directory Publishing Purpose Rapid Access to Intervention Development Registries Relative (related person)Reporting Research Research Design Research Personnel Resources Role Running Salaries and Fringe Benefits Science Serum Services Shared Resource Cancer Center Site Specific qualifier value Statistical Methods Statistical Models Statistical Study Sum Survival Analysis Techniques Telephone Testing Texas Time Tissues Travel Universities University of Texas M D Anderson Cancer Center Voice Wages Work Writing anticancer research base cluster computing comparative genomic hybridization cost design experience foot high throughput analysis human embryonic stem cell innovation killings malignant breast neoplasm medical specialties member oncology performance site professor prognostic programs research study response sarcoma software development statistics symposium trait

项目摘要

The role of the Biostatistics Core in this Program Project is to support the clinical and laboratory based projects. This includes collaboration with investigators in the design and conduct of research studies, statistical modeling, hypothesis formulation and testing, and data analysis. There are three major activities: (1) consultation and collaboration in the planning, conduct, analysis and reporting of clinical trials in AML; (2) consultation and collaboration with laboratory research investigators evaluating the cellular and molecular basis of response, to identify specific biological markers; (3) evaluation of the prognostic significance of these biological markers, based on their presence or quantitative levels over time in the patient; and (4) consultation in the design of high throughput experimentsand analysis of the high throughput data. The Biostatistics Core has been well established and currently carries out all of the above activities on an ongoing basis.

生物统计学核心在该计划项目中的作用是支持临床和实验室项目。这包括与研究人员在研究和进行研究研究中的合作，统计建模，假设制定和测试以及数据分析。有三个主要活动：（1）在AML的临床试验计划，进行，分析和报告中进行咨询与协作；（2）与评估细胞和分子的实验室研究研究人员进行咨询和合作反应的基础，以识别特定的生物标记；（3）评估预后意义这些生物标志物基于患者的存在或定量水平；（4）在高吞吐量实验和高吞吐量数据的高吞吐量实验和分析时进行咨询。这生物统计学核心已经建立了良好，目前正在从事上述所有活动持续的基础。