Renal Molecular Cell Biology Training Program

肾分子细胞生物学培训项目

• 批准号: 7256876
• 负责人: ROBERT L BACALLAO
• 金额: $ 10万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7256876
• 关键词: Cellular biology; Kidney; Molecular; Training Programs

DESCRIPTION (provided by applicant):This is a proposal for a nephrology training program whose goal is to develop physicians with the requisite skills to perform basic, translational and clinical research in nephrology. A unifying theme for the program is advance light microscopy imaging techniques which is utilized to study four broad areas;) ischemia induced renal epithelial injury, 2) autosomal dominant polycystic kidney disease, 3) metabolic bone disease and 4) epithelial cell polarity. This program seeks to increase the dynamic interactions of a highly motivated faculty that has created a highly interactive, intellectually excitng environment. This program now offers three pathways to train physician-scientist, 1) a nephrology training program with a two-year basic research requirement, 2) a PhD degree granting program offered through the Department of Medicine's ABIM sponsored Clinician Investigator program and 3) a Masters in Clinical Research degree program. The later program is designed to train fellows in the details of performing and completing clinical research projects. This program from its inception has utilized combined faculty of MDs and PhDs working on common research themes. The resulting environment has resulted in enhanced training for physician-scientists. MDs provide insights into disease-related processes while PhDs offer improved problem solving insights and rigourous evaluation of scientific data. This proposal seeks to build upon a record to training physician-scientists and to enhance the educational opportunities for nephrology trainees. We envision recruitment of MDs and MD/PhDs with an interest in renal disease pathogensis and molecular cell biology. Depending upon the training pathway selected, a minimum of three years will be spent in the program and up to seven years may be spent in the pursuit of a PhD degree along with Nephrology subspeciality training. This highly interactive group of physicians and PhDs share common interest in renal pathophysiology. The program is idealy suited to effectively recruit under represented minorities, since we have minority role models on the faculty. This grant will extend the working relationships of our faculty with the departments of Cellular and Integrative Physiology, Biochemistry/Molecular Biology, Microbiology/Immunology and Anatomy/Cell Biology. By doing so, our faculty will increase their interactions with graduate students, post-doctoral fellows, medical students and medicine residents. We propose to train three postdoctoral fellows each fiscal year.

描述（由申请人提供）：这是一项肾病学培训计划的提案，其目标是培养具备进行肾病学基础、转化和临床研究所需技能的医生。该计划的统一主题是先进的光学显微镜成像技术，用于研究四个广泛的领域：）缺血引起的肾上皮损伤，2）常染色体显性多囊肾病，3）代谢性骨病和4）上皮细胞极性。该项目旨在增加积极主动的教师之间的动态互动，创造出一个高度互动、激发智力的环境。该计划现在提供三种培训医师科学家的途径，1）具有两年基础研究要求的肾病学培训计划，2）通过医学部的 ABIM 赞助的临床研究员计划提供的博士学位授予计划，以及 3）硕士学位临床研究学位课程。后面的项目旨在培训研究员执行和完成临床研究项目的细节。该项目从一开始就利用了从事共同研究主题的医学博士和博士学位的联合教师。由此产生的环境加强了对医师科学家的培训。医学博士提供对疾病相关过程的见解，而博士学位则提供改进的解决问题的见解和对科学数据的严格评估。该提案旨在建立培训医师科学家的记录，并增加肾病学学员的教育机会。我们设想招募对肾脏疾病发病机制和分子细胞生物学感兴趣的医学博士和医学博士/博士。根据所选的培训途径，该计划至少需要三年时间，最长可能需要七年时间来攻读博士学位以及肾脏病学亚专业培训。这个高度互动的医生和博士小组对肾脏病理生理学有着共同的兴趣。该计划非常适合有效地招募代表性不足的少数族裔，因为我们的教职人员中有少数族裔的榜样。这笔赠款将扩大我们的教师与细胞和综合生理学、生物化学/分子生物学、微生物学/免疫学和解剖学/细胞生物学系的工作关系。通过这样做，我们的教师将增加与研究生、博士后研究员、医学生和医学住院医师的互动。我们建议每个财政年度培养三名博士后。