The Gastrointestinal Epithelium Conference - Interface with the Outside World

胃肠上皮会议 - 与外界的接口

• 批准号: 10753753
• 负责人: Mark R Frey
• 金额: $ 4.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753753
• 关键词: Area; Autophagocytosis; Basic Science; Biology; Biomedical Research; Cell Communication; Cells; Cellular biology; Clinical; Collaborations; Colon; Committee Members; Communication; Communities; Complement; Consultations; Data; Development; Developmental Biology; Digestive System Disorders; Diné Nation; Discipline; Disease; Drug Delivery Systems; Educational workshop; Ensure; Environment; Epithelium; Esophagus; Female; Friends; Funding; Future; Gastrointestinal Physiology; Gastrointestinal tract structure; Goals; Guanosine Triphosphate Phosphohydrolases; Health; Homeostasis; Hypoxia; In Vitro; Individual; Inflammation; Inflammatory Bowel Diseases; Intestines; Investigation; Laboratories; Length; Malignant Neoplasms; Mentorship; Metabolism; Methodology; Methods; Microbiology; Molecular; Molecular Biology; National Institute of Diabetes and Digestive and Kidney Diseases; Natural regeneration; Neurobiology; Oral; Parents; Participant; Physicians; Physiological; Process; Proliferating; Reagent; Request for Applications; Research; Research Personnel; Resolution; Role; Schedule; Science; Scientist; Sensory; Signal Transduction; Signaling Molecule; Site; Small Intestines; Stomach; Students; Systemic disease; Time; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; bench to bedside; career; career development; cell motility; clinically significant; design; gastrointestinal; gastrointestinal epithelium; genetic manipulation; in vivo Model; injury and repair; innovation; insight; interest; intestinal barrier; lectures; live cell imaging; meetings; member; pathogen; posters; programs; response; response to injury; stem cell homeostasis; stem cells; symposium; trafficking

Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Epithelium: Interface with the Outside World” that is scheduled for September 17-21, 2023 in Steamboat Springs, CO. The meeting will convene a diverse group of speakers, including many women, underrepresented minorities, and young investigators, to discuss the biology of the gastrointestinal epithelium and its role in homeostasis and disease. The keynote presentations plus seven lecture sessions will address gastrointestinal stem cell homeostasis and plasticity in response to injury/disease; development and differentiation of the epithelium; injury repair, proliferation, and regeneration in the esophagus, stomach, small intestine, and colon; cell-cell interactions; host-pathogen interactions; intestinal barrier; hypoxia, inflammation and IBD; and cancer. Ample time will be set aside for discussions amongst participants, and the presentation of unpublished data will be prioritized. There will also be two poster sessions as well as several career development activities for early career investigators and trainees, as well as opportunities to promote the visibility of these individuals who represent the future of the field. We have assembled an innovative program with committed participation from leaders with diverse expertise within GI-related research fields. Overall, in an intimate and secluded setting that encourages informal interactions between scientists at all levels, we provide an innovative approach to the exchange of ideas and synthesis of science that will move the field of GI research forward. The conference will have high impact as the program spans basic science discovery to clinical significance for GI health and disease. It is therefore expected that the meeting will provide new insights not only into basic gastrointestinal physiology, neurobiology, developmental biology and microbiology, but also how to treat, and ultimately cure, a wide variety of digestive disease states.

项目摘要/摘要 该申请要求为FaseB科学研究会议提供部分支持，标题为“胃肠道 上皮：与外界的界面”定于2023年9月17日至21日在汽船上 Springs，CO。会议将召集包括许多妇女在内的一群演讲者，人数不足 少数民族和年轻的研究人员讨论胃肠道上皮的生物学及其在 稳态和疾病。主题演讲以及七次讲座将解决胃肠道 干细胞稳态和响应损伤/疾病的可塑性；发展和差异 上皮；食管，摊位，小肠和结肠的损伤修复，增殖和再生； 细胞 - 细胞相互作用；宿主病原体相互作用；肠壁;缺氧，感染和IBD；和癌症。 将留出足够的时间来进行参与者之间的讨论，未发表的数据的介绍将 优先考虑。还将有两个海报会议以及早期的几项职业发展活动 职业调查人员和学员，以及促进这些人的知名度的机会 代表该领域的未来。我们组装了一个创新计划，并从 在与GI相关的研究领域中具有潜水员专业知识的领导者。总体而言，在一个亲密而分开的环境中 这鼓励了各级科学家之间的非正式互动，我们为 思想的交流和科学的综合，将推动GI研究领域的发展。会议将 由于该计划跨越基础科学发现对胃肠道健康的临床意义，并且具有很大的影响 疾病。因此，预计会议将不仅为基本胃肠道提供新的见解 生理学，神经生物学，发育生物学和微生物学，以及如何治疗并最终治愈 多种消化系统状态。