Renal Molecular Cell Biology Training Program

肾分子细胞生物学培训项目

• 批准号: 6735608
• 负责人: ROBERT L BACALLAO
• 金额: $ 19.58万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6735608
• 关键词: Renal; Molecular; Cell; Biology; Training

DESCRIPTION (provided by applicant):This is a proposal for a nephrology training program whose goal is to develop physicians with the requisite skills to perform basic, translational and clinical research in nephrology. A unifying theme for the program is advance light microscopy imaging techniques which is utilized to study four broad areas;) ischemia induced renal epithelial injury, 2) autosomal dominant polycystic kidney disease, 3) metabolic bone disease and 4) epithelial cell polarity. This program seeks to increase the dynamic interactions of a highly motivated faculty that has created a highly interactive, intellectually excitng environment. This program now offers three pathways to train physician-scientist, 1) a nephrology training program with a two-year basic research requirement, 2) a PhD degree granting program offered through the Department of Medicine's ABIM sponsored Clinician Investigator program and 3) a Masters in Clinical Research degree program. The later program is designed to train fellows in the details of performing and completing clinical research projects. This program from its inception has utilized combined faculty of MDs and PhDs working on common research themes. The resulting environment has resulted in enhanced training for physician-scientists. MDs provide insights into disease-related processes while PhDs offer improved problem solving insights and rigourous evaluation of scientific data. This proposal seeks to build upon a record to training physician-scientists and to enhance the educational opportunities for nephrology trainees. We envision recruitment of MDs and MD/PhDs with an interest in renal disease pathogensis and molecular cell biology. Depending upon the training pathway selected, a minimum of three years will be spent in the program and up to seven years may be spent in the pursuit of a PhD degree along with Nephrology subspeciality training. This highly interactive group of physicians and PhDs share common interest in renal pathophysiology. The program is idealy suited to effectively recruit under represented minorities, since we have minority role models on the faculty. This grant will extend the working relationships of our faculty with the departments of Cellular and Integrative Physiology, Biochemistry/Molecular Biology, Microbiology/Immunology and Anatomy/Cell Biology. By doing so, our faculty will increase their interactions with graduate students, post-doctoral fellows, medical students and medicine residents. We propose to train three postdoctoral fellows each fiscal year.

描述（由申请人提供）：这是针对肾脏病培训计划的一项建议，其目的是开发具有执行肾脏科基本，转化和临床研究必要技能的医生。该程序的一个统一主题是先进的光学显微镜成像技术，用于研究四个广泛的领域；）缺血诱导的肾上皮损伤，2）常染色体显性多囊肾脏疾病，3）代谢骨病和4）上皮细胞极性。该计划旨在增加一个高度积极进取的教师的动态互动，该教师创造了高度互动，智力上的环境。该计划现在提供了三个培训医师科学家的途径，1）一项具有两年基础研究要求的肾脏病培训计划，2）通过医学院Abim赞助的临床研究员计划和3）临床研究学位课程的硕士学位。后来的计划旨在训练研究员，以表演和完成临床研究项目的细节。该计划从成立开始就利用了在共同研究主题上工作的MDS和PHD的合并学院。由此产生的环境导致对医师科学家的培训增强。 MD提供了有关与疾病相关过程的见解，而博士学位提供了改进的解决问题的见解和对科学数据的严格评估。该建议旨在以培训医师科学家的记录为基础，并增强肾脏科学员的教育机会。我们设想对MDS和MD/PHD的招募，对肾脏疾病病原体和分子细胞生物学感兴趣。根据所选的培训途径，该计划至少要花费三年的时间，并且最多可以花费七年的时间来追求博士学位以及肾脏科专业培训。这个高度互动的医师和博士学位在肾脏病理生理学中具有共同的兴趣。该计划非常适合在代表的少数群体下有效招募，因为我们在教职员工上有少数群体榜样。该赠款将扩大我们的教职员工与细胞和综合生理学，生物化学/分子生物学，微生物学/免疫学和解剖学/细胞生物学部门的工作关系。通过这样做，我们的教师将增加与研究生，博士后研究员，医学生和医学居民的互动。我们建议每个会计年度培训三个博士后研究员。