Investigation of novel methods to study the survival of foot-and-mouth disease virus in aerosols

研究口蹄疫病毒在气溶胶中存活的新方法

• 批准号: 2885948
• 金额: --
• 依托单位: University of Bristol
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2885948
• 关键词: Investigation; novel; methods; study; survival

This project will use recently developed laboratory methods to explore how the survival of FMDV in aerosols varies between strains, and how survival in aerosols is influenced by environmental conditions. Of particular interest will be examining characteristic properties of contemporary FMDVstrains from emerging lineages, where geographic ranges have been expanded, and determining differences that exist between strains from diverse geographical regions. FMDV strains for use in experimental studies will be selected based on relevant epidemiology in the global context and availability of stocks via the World Reference Laboratories at The Pirbright Institute. Data generated in experimental work will highlight the risks associated with aerosol transmission of FMDV and inform mitigation and control strategies.

该项目将利用最近开发的实验室方法来探索口蹄疫病毒在气溶胶中的存活率在不同菌株之间有何差异，以及气溶胶中的存活率如何受到环境条件的影响。特别令人感兴趣的是研究来自新兴谱系的当代口蹄疫病毒株的特征，这些谱系的地理范围已经扩大，并确定来自不同地理区域的病毒株之间存在的差异。用于实验研究的口蹄疫病毒株将根据全球背景下的相关流行病学以及皮尔布赖特研究所世界参考实验室的库存可用性来选择。实验工作中产生的数据将强调与口蹄疫气溶胶传播相关的风险，并为缓解和控制策略提供信息。