Tulane/LSU HIV/AIDS Clinical Trials Networks Unit

杜兰大学/路易斯安那州立大学艾滋病毒/艾滋病临床试验网络单位

基本信息

批准号：
7095654
负责人：
RUSSELL B. VAN DYKE
金额：
$ 49.92万
依托单位：
TULANE UNIVERSITY OF LOUISIANA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-02-08 至 2007-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7095654
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adolescent Adult Area Behavioral Charities Child Clinical Management Clinical Research Clinical Trials Clinical Trials Network Clinical Trials-Pediatric AIDS Collaborations Conduct Clinical Trials HIV HIV Infections Health Sciences Hepatitis C virus Hospitals Human Papillomavirus Inpatients Institution International Maternal Pediatric Adolescent AIDS Clinical Trials Group Louisiana Medical center Morbidity - disease rate Opportunistic Infections Outpatients Patients Pharmacology Population Prevention Recording of previous events Research Retrovirology Schools Site Teaching Hospitals Translational Research Tuberculosis Universities Vaccine Research Vertical Disease Transmission Women&apos s Health base clinical research site drug development improved prevent programs research and development transmission process

项目摘要

DESCRIPTION (provided by applicant): The Tulane/LSU HIV/AlDS Clinical Trials Unit (CTU) will be based in a single institution, The Medical Center of Louisiana in New Orleans (MCLNO), formally known as Charity Hospital of New Orleans. The CTU represents a collaborative effort between the Tulane and Louisiana State University Health Sciences Centers. Both medical centers utilize the MCLNO as their primary teaching hospital and there is a long history of collaboration between the two schools in HIV treatment and research programs based at MCLNO. The CTU is comprised of two clinical research sites (CRS), a Maternal/Child CRS and an Adult CRS. The Maternal/Child CRS represents the current Pediatric AIDS Clinical Trials Unit. The Maternal/Child CRS is affiliated with the IMPAACT Network, having been selected as one of its ten highly preferred domestic sites. It will focus on the four priority areas being addressed by the IMPAACT Network: (1) Vaccine Research and Development; (2) Translational Research and Drug Development; (3) Optimization of Clinical Management, Including Co-Morbidities; and (4) Prevention of Mother-to-Child Transmission of HIV. The Maternal/Child CRS brings to IMPAACT a strong history of scientific contribution to the PACTG with expertise in maternal-to-child transmission, the HIV-infected adolescent and behavioral aspects of HIV. The Adult CRS consists of the former Tulane/LSU Adult AIDS Clinical Trials Unit. It is not affiliated with a network and will focus on one priority area: Translational Research and Drug Development. The adult CRS is ideally suited to address this important priority area with access to a large inpatient and outpatient population of HIV patients, use of the Tulane/LSU General Clinical Research Center, and expertise in pharmacology, drug development, retrovirology, woman's health, and opportunistic infections including tuberculosis, hepatitis C virus, and HPV. The CTU will conduct clinical trials developed by the IMPAACT Network and an Adult Network in order to develop new and improved ways to treat and prevent HIV infection in adults and children. ADMINISTRATIVE COMPONENT:

描述（由申请人提供）：杜兰大学/路易斯安那州立大学 HIV/AlDS 临床试验中心 (CTU) 将设在一个机构，即新奥尔良路易斯安那州医疗中心 (MCLNO)，正式名称为新奥尔良慈善医院。 CTU 代表了杜兰大学健康科学中心和路易斯安那州立大学健康科学中心之间的合作成果。两个医疗中心均将 MCLNO 作为其主要教学医院，两所学校在 MCLNO 的艾滋病毒治疗和研究项目方面有着悠久的合作历史。 CTU 由两个临床研究中心 (CRS) 组成，即母婴 CRS 和成人 CRS。母婴 CRS 代表当前的儿科艾滋病临床试验单位。母婴 CRS 隶属于 IMPAACT Network，被选为国内十大首选网站之一。它将重点关注 IMPAACT 网络正在解决的四个优先领域：(1) 疫苗研究和开发； (2) 转化研究与药物开发； (3) 优化临床管理，包括合并症； (4) 预防艾滋病毒母婴传播。母婴 CRS 为 IMPAACT 带来了对 PACTG 的悠久科学贡献，在母婴传播、艾滋病毒感染青少年和艾滋病毒行为方面拥有专业知识。成人 CRS 由前杜兰大学/路易斯安那州立大学成人艾滋病临床试验组组成。它不隶属于任何网络，并将专注于一个优先领域：转化研究和药物开发。成人 CRS 非常适合解决这一重要的优先领域，可接触大量住院和门诊 HIV 患者群体，利用杜兰/路易斯安那州立大学普通临床研究中心，并拥有药理学、药物开发、逆转录病毒学、妇女健康和艾滋病毒方面的专业知识。机会性感染，包括结核病、丙型肝炎病毒和HPV。 CTU 将开展由 IMPAACT 网络和成人网络开发的临床试验，以开发新的和改进的方法来治疗和预防成人和儿童的艾滋病毒感染。行政部分：