Institutional Training for Pediatricians

儿科医生机构培训

• 批准号: 7073399
• 负责人: George J Dover
• 金额: $ 19.24万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7073399
• 关键词: Institutional; Training; Pediatricians

DESCRIPTION (provided by applicant): The goal of the Institutional NRSA at Johns Hopkins University is to train pediatric residents and fellows to become successful junior faculty whose primary research interest is in the diagnosis, pathogenesis and treatment of genetic and acquired disorders in children. The program recruits and trains individuals to use the most modem techniques in genetics, genomics, molecular biology and the principles of clinical research to address, pathogenesis, diagnoses, and therapy for pediatric disease. With the completion of the human genome sequence, a new challenge will be for pediatric researchers to address questions regarding multiple genes and the function of their encoded proteins. The researchers of the next generation will try to understand how multiple proteins function in pathways and how these pathways interact with the environment subsequently leading to human phenotypes, which often vary among individuals. It is our goal to provide young academic pediatricians with the training necessary in molecular and cell biology and in genomic sciences to improve child health. The program will utilize as mentors a variety of investigators both in clinical and basic science departments who are well versed in training young clinician scientists. The training program with offer three possible tracks; a program that integrates the pediatric residency training experience with a dedicated research year and subsequent pediatric subspecialty fellowship research experience (Track A), a two year research fellowship program following the completion of the first year of a clinical pediatric subspecialty fellowship (Track B), and an extended three year research fellowship (Track C). A formal curriculum that combines core courses, required for all trainees, in Responsible Conduct of Research, Investigator Training in Animal Use, and Maturation into a Independent Scientist are combined where appropriate for the individual trainee with a variety of technical courses (bioinformatics, genomics, principles of clinical research, and Graduate Training in Clinical Investigation). In addition to the laboratories of their mentors, the environment of the program includes additional resources including a NIH-funded Pediatric Clinical Research Unit (inpatient and outpatient), Genetics Core Facility for DNA sequencing and genetic linkage mapping, Transgenic Animal Facility, Core Microscopy and Mass Spectrometry Facilities, and collaborative individual investigator research programs which in the pediatric subspecialties alone include more than 60 million dollars of NIH-funded total direct costs.

描述（由申请人提供）：约翰·霍普金斯大学的机构NRSA的目标是培训儿科居民和研究员，成为成功的初级教师，其主要研究兴趣是对儿童的遗传和遗传性疾病的诊断，发病和治疗。该计划招募并培训个人，以使用遗传学，基因组学，分子生物学和临床研究原理中的最高现代技术，以解决儿科疾病的解决，发病机理，诊断和治疗。随着人类基因组序列的完成，儿科研究人员将解决有关多个基因及其编码蛋白功能的问题的新挑战。下一代的研究人员将试图了解多种蛋白质在途径中的作用，以及这些途径如何与环境相互作用，随后导致人类表型，这种表型在个体之间通常会有所不同。我们的目标是为年轻的学术儿科医生提供分子和细胞生物学以及基因组科学的必要培训，以改善儿童健康。该计划将在临床和基础科学部门的各种研究人员中充当培训年轻临床医生科学家的各种研究人员。培训计划提供三个可能的曲目；一项计划，将儿科居住培训经验与专门研究年和随后的小儿群体研究生研究经验（TRACK A）相结合，这是一项为期两年的研究奖学金计划，该计划完成了临床小儿专科临床专业奖学金第一年之后（轨道B），以及长期的三年研究研究奖学金（TRACK B），以及一项长达三年的研究奖学金（Track Charthip C）（轨道C）。将所有学员所需的核心课程，动物使用的研究人员培训以及成熟到独立科学家的核心课程相结合的正式课程，适用于具有各种技术课程的个人学员（生物信息学，基因组学，临床研究原理和临床研究研究生培训）的情况。除了导师的实验室外，该计划的环境还包括其他资源，包括NIH资助的小儿临床研究单元（住院和门诊），用于DNA测序的遗传学核心设施以及遗传链接映射，遗传链接图，核心动物设施，核心显微镜和群众群体研究中的核心群体和协作式的群体研究，这些计划中的阶级和协作的人群中的阶级和协作式群体，以及在同步中的阶级，以及在协作中的阶级，并在NIH资助的总直接成本。