SOUTH AFRICAN MEN HEALTH PROMOTION PROJECT

南非男性健康促进项目

• 批准号: 7231516
• 负责人: JOHN BARTON JEMMOTT
• 金额: $ 89.2万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7231516
• 关键词: AIDS education /prevention; African; HIV infections; antiinfective agents; behavioral /social science research tag; belief; clinical research; cognitive behavior therapy; computer human interaction; condoms; focus groups; health behavior; high risk behavior /lifestyle; human subject; international cooperation; interview; male; questionnaires; safe sex /sex abstinence; sex behavior; sex partner; sexually transmitted diseases; videotape /videodisc

DESCRIPTION (provided by applicant): This application is submitted in response to Program Announcement PA-05-033, "Men's Heterosexual Behavior and HIV Infection." The broad, long-term objective is to identify interventions to dissuade South African men from engaging in behaviors that increase their risk for sexually transmitted diseases (STDs), including HIV. The Specific Aims are to (a) test the efficacy of an HIV/STD risk reduction intervention in increasing consistent condom use, (b) examine community-level and individual-level variables that may moderate the efficacy of the intervention, and (c) identify mediators that account for the intervention's effects on consistent condom use. The design of the study is a cluster randomized controlled trial. We will stratify Black neighborhoods near East London, South Africa on key characteristics and match them in pairs. We will randomly select 12 matched-pairs and within each pair, randomly assign the neighborhoods to one of two small-group interventions led by a male facilitator: a 6-hour HIV/STD Risk-Reduction Intervention or a 6- hour health promotion intervention concerning health issues unrelated to sexual behavior that will serve as the control condition. We will enroll in the trial 60 men from each neighborhood, for a total of 1,440 participants. The approach draws on social cognitive theory, the theory of reasoned action/theory of planned behavior, and the applicant's preliminary studies with men from the study population. The primary outcome is self-reported consistent condom use in the previous 3 months collected at baseline and 6 and 12 months post-intervention via audio-computer-assisted self-interviewing (ACASI). Secondary outcomes include number of sexual partners, frequency of unprotected sexual intercourse, condom use at last intercourse, and theoretical variables hypothesized to mediate intervention effects, including intentions, beliefs, and self- efficacy. The proposed research has great public health relevance because, while about one-half the cases of HIV/AIDS worldwide are linked to sexual relations between men and women, only a few studies have tested HIV/STD risk-reduction interventions specific to men. This research will test the efficacy of such an intervention in a developing country with some of the highest rates of heterosexually transmitted HIV infection in the world. Moreover, it will contribute to scientific knowledge about the kinds of men with whom it is most efficacious and the factors that account for its efficacy.

描述（由申请人提供）：该申请是根据计划公告PA-05-033，“男性的异性行为和艾滋病毒感染”提交的。广泛的长期目标是确定干预措施，以阻止南非男性从事行为，从而增加其性传播疾病（STD）（包括艾滋病毒）的风险。具体目的是（a）测试艾滋病毒/性病风险降低干预措施在增加一致的避孕套中的功效，（b）检查社区级别和个体级别的变量，这些变量可能会缓解干预措施的疗效，以及（c）识别出对干预效果一致避孕套使用的介体。该研究的设计是一项群集随机对照试验。我们将以关键特征对南非东伦敦东部附近的黑人社区进行分层，并成对匹配。我们将随机选择12对匹配对，在每对中，将社区随机分配给由男性促进者领导的两个小组干预措施之一：6小时的HIV/STD风险降低干预措施或6小时的健康促进干预措施，与与性行为无关的健康问题无关的健康问题，这将作为控制条件。我们将参加来自每个社区的60名男子，共有1,440名参与者。该方法借鉴了社会认知理论，计划行为的理论理论/计划行为理论以及申请人与研究人群中的男性的初步研究。主要结果是在基线的前3个月内通过音频计算机辅助自我接触（ACASI）收集的前三个月（ACASI）自我报告的一致避孕套。次要结果包括性伴侣的数量，不受保护的性交的频率，最终性交的避孕套以及假设介导干预效应的理论变量，包括意图，信念和自我效能。拟议的研究具有很大的公共卫生相关性，因为虽然全世界的艾滋病毒/艾滋病案件大约与女性之间的性关系有关，但只有少数研究已经测试了男性特定的HIV/STD风险减少干预措施。这项研究将测试这种干预措施对世界上异性传播艾滋病毒感染率最高的发展中国家的疗效。此外，它将有助于科学知识，以了解其最有效的男人，以及造成其功效的因素。