Integrative Examination of Comorbidity with ADHD

多动症合并症的综合检查

• 批准号: 7055236
• 负责人: HEATHER E VOLK
• 金额: $ 0.5万
• 依托单位: SAINT LOUIS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2006-07-10
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7055236
• 关键词: alcoholism /alcohol abuse; attention deficit disorder; behavioral /social science research tag; behavioral genetics; child psychology; clinical research; comorbidity; conduct disorder; depression; disease /disorder etiology; disease /disorder proneness /risk; gene environment interaction; health behavior; human data; mathematical model; mental disorder diagnosis; mental health epidemiology; model design /development; molecular genetics; oppositional defiant disorder; predoctoral investigator; psychopathology; smoking; statistics /biometry

DESCRIPTION (provided by applicant): This pre-doctoral research support application is structured to prepare the applicant to compete for a research-oriented faculty position in psychiatric and genetic epidemiology. Specifically, training & supervised research experience will focus on combining epidemiologic, statistic, & behavior genetic methods to study the etiology of child psychiatric disorder co-occurrence. Disorder clustering, severity, shared genetic influence, & outcomes will be examined to assess the relationship of comorbid psychopathology with Attention Deficit Hyperactivity Disorder (ADHD). ADHD is a multi-dimensional disorder characterized by symptoms of hyperactivity, impulsivity, & inattention, thus, externalizing & internalizing disorders may co-occur differentially. Genes or the environment both likely influence the etiology of these disorders & their permutations in different ways. This pre-doctoral fellowship award will allow the applicant to: 1) conduct secondary data analysis of two existing datasets to systematically examine comorbidity with ADHD & influences on disorder clustering employing contemporary statistical methodology & 2) complete coursework & training in these methods, psychiatric epidemiology, & gain an introduction to molecular genetics.

描述（由申请人提供）：该博士前研究支持申请的结构是为申请人做好准备，以竞争精神病和遗传流行病学领域的研究导向的教职员工。具体而言，培训和监督研究经验将集中于将流行病学，统计和行为遗传学方法相结合，以研究儿童精神疾病的病因。将检查混乱聚类，严重程度，共同的遗传影响和结果，以评估合并症心理病理学与注意力缺陷多动障碍（ADHD）的关系。多动症是一种多维疾病，其特征是多动症，冲动性和注意力不集中的症状，因此，外在化和内在化疾病可能会差异化。基因或环境都可能以不同的方式影响这些疾病及其排列的病因。该博士前奖学金奖项将允许申请人进行：1）对两个现有数据集进行二级数据分析，以系统地检查合并症，并使用ADHD和对混乱聚类的影响采用当代统计学方法和2）在这些方法，精神病学流行病学以及对分子植物学的简介中进行完整的课程和培训。

项目成果

Comorbidity between ADHD and symptoms of bipolar disorder in a community sample of children and adolescents.

儿童和青少年社区样本中多动症和双相情感障碍症状之间的合并症。

• DOI: 10.1375/183242705774310105
• 发表时间: 2005
• 期刊: Twin research and human genetics : the official journal of the International Society for Twin Studies
• 作者: Reich,Wendy;Neuman,RosalindJ;Volk,HeatherE;Joyner,CynthiaA;Todd,RichardD
• 通讯作者: Todd,RichardD

The XVth World Congress of Psychiatric Genetics, October 7-11, 2007: Rapporteur summaries of oral presentations.

第十五届世界精神病遗传学大会，2007 年 10 月 7-11 日：报告员口头报告摘要。

• DOI: 10.1002/ajmg.b.30711
• 发表时间: 2008
• 期刊: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
• 作者: Alkelai,Anna;Baum,Amber;Carless,Melanie;Crowley,James;Dasbanerjee,Tania;Dempster,Emma;Docherty,Sophia;Hare,Elizabeth;Galsworthy,MichaelJ;Grover,Deepak;Glubb,Dylan;Karlsson,Robert;Mill,Jonathan;Sen,Srijan;Quinones,MarlonP;Va
• 通讯作者: Va

Genetic influences on free and cued recall in long-term memory tasks.

遗传对长期记忆任务中自由回忆和提示回忆的影响。

• DOI: 10.1375/183242706778553462
• 发表时间: 2006
• 期刊: Twin research and human genetics : the official journal of the International Society for Twin Studies
• 作者: Volk,HeatherE;McDermott,KathleenB;Roediger3rd,HenryL;Todd,RichardD
• 通讯作者: Todd,RichardD