5th Intn'l.Symp.:Meniere's Disease/Inner Ear Homeostasis

第 5 种国际症状：梅尼埃病/内耳稳态

• 批准号: 6888376
• 负责人: David J. Lim
• 金额: $ 3万
• 依托单位: HOUSE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6888376
• 关键词: Meniere' s disease; endolymph; labyrinth; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): Over the last five years much progress has been made in our understanding of the pathogenesis of Meniere's disease (MD) and the important role that disturbances of inner ear fluid homeostasis play in a variety of hearing and balance problems. Through studies of mouse models, a number of inner ear disorders affecting hearing have been identified that involve defects in genes that regulate ion channels and ion and fluid regulation; however, a bridge from these experimental studies to clinical studies is lacking. We are seeking NIH funds to support, in part, the Fifth International Symposium on Meniere's Disease and Inner Ear Homeostasis Disorders to be held April 2-5, 2005, at the Universal Hilton, Universal City, California. The expected number of attendees is 250-300 otolaryngologists, pediatricians, general practitioners, and basic scientists (cell biologists, immunologists, molecular biologists, epidemiologists, etc.) from around the world. The Symposium will consist of three Special Lectures on selected topics of importance, five Mini-Symposia, two Panel Discussions and contributed papers (oral and poster presentations). A discussion will follow each presentation. The aims of the Fifth International Symposium on Meniere's Disease and Inner Ear Homeostasis Disorders are: 1) to review new discoveries that have been made in basic and clinical research since the last International Symposium on Meniere's Disease and Inner Ear Homeostasis held in Paris, February, 1999; 2) to critically review recent discoveries in epidemiology, genetics, microbiology, immunology, cell and molecular biology, pathogenesis, prevention, diagnosis management and sequelae of MD; 3) to provide a scientific forum for basic and clinical scientists and physicians in order to enhance interaction and collaboration and to take advantage of new research opportunities; and 4) to widely disseminate information by publication.

描述（由申请人提供）：在过去五年中，我们对梅尼埃病（MD）的发病机制以及内耳液体稳态紊乱在各种听力和平衡问题中所起的重要作用的理解取得了很大进展。通过对小鼠模型的研究，已经发现许多影响听力的内耳疾病与调节离子通道以及离子和液体调节的基因缺陷有关。然而，缺乏从这些实验研究到临床研究的桥梁。 我们正在寻求 NIH 资金来部分支持将于 2005 年 4 月 2 日至 5 日在加利福尼亚州环球城环球希尔顿酒店举行的第五届梅尼埃病和内耳稳态紊乱国际研讨会。预计参加人数为250-300名来自世界各地的耳鼻喉科医生、儿科医生、全科医生和基础科学家（细胞生物学家、免疫学家、分子生物学家、流行病学家等）。研讨会将包括三场关于选定重要主题的特别讲座、五场小型研讨会、两场小组讨论和投稿论文（口头和海报展示）。每次演讲后都会进行讨论。 第五届梅尼埃病和内耳稳态紊乱国际研讨会的目的是： 1) 回顾自上一次梅尼埃病和内耳稳态紊乱国际研讨会自 2 月在巴黎举行以来在基础和临床研究中取得的新发现， 1999； 2）批判性地回顾MD的流行病学、遗传学、微生物学、免疫学、细胞和分子生物学、发病机制、预防、诊断管理和后遗症的最新发现； 3）为基础和临床科学家和医生提供一个科学论坛，以加强互动与合作并利用新的研究机会； 4）通过出版物广泛传播信息。