Core Center: NIDCD Research Core Center P30

核心中心：NIDCD研究核心中心P30

• 批准号: 7850374
• 负责人: David J. Lim
• 金额: $ 13.64万
• 依托单位: HOUSE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-17 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7850374
• 关键词: Core; Center; NIDCD; Research; P30

DESCRIPTION (provided by applicant): The HEI Core Center for Hearing Research aims to support and facilitate research, foster collaborations and set new research directions in the following two areas: 1) engineering, and 2) imaging/morphology. Core B: Engineering - The Engineering Core will develop and maintain expertise in rapidly changing technologies to support new and innovative enabling technologies for scientific applications: digital signal processing (DSP), communication interfaces, and controllers. The Core will also interact with project-specific engineers to provide core hardware and software components in these areas for integration into research projects. Core C: Imaging and Morphology - aims to provide state-of-the-art, intravital imaging, morphology and microscopy services and training to HEI scientists. Such services include inspection and maintenance of all imaging equipment, image storage and analysis, morphometry and training. The addition of a histology technician will help towards the achievement of this objective. The addition of a full time confocal technician is particularly important since we are in the process of purchasing two new Laser Scanning Confocal microscopes with increased functionality to replace the one we originally purchased 10 years ago. The Core will perform inspection and maintenance of all imaging and tissue processing equipment. The Core will also encourage collaboration and dissemination of information about advances in the field of imaging. Core B Engineering Core Director: Robert Shannon, Ph.D. DESCRIPTION (provided by applicant): The HEI Engineering core provides highly technical engineering expertise to enable cutting edge technical solutions to practical problems faced by a diverse array of scientists. Engineering solutions are episodic in nature, requiring several months of highly skilled engineering expertise, but only infrequently. Individual Investigators generally do not have sufficient engineering needs on a continuing basis to justify full-time engineering personnel. The Engineering Core will maintain expertise in rapidly changing technologies to support new and innovative enabling technologies for scientific applications. Modern auditory research involving auditory prostheses and hearing assessment systems depends heavily on real-time processing of digital information. The engineering core will maintain expertise in real time digital signal processing (DSP) hardware and software (Aim 1). The engineering core will develop and maintain expertise on the communication interfaces such as USB and IEEE 1394 with host computers and specialized hardware/software platforms for laboratory instrumentation (Aim 2). Many experimental applications require precise triggering and coordination of multiple pieces of equipment, on time scales as short as microseconds and for spatial resolution of image data in the micron range. The engineering core will develop and maintain hardware and software to allow precision control of diverse equipment (Aim 3).

描述（由申请人提供）：HEI 听力研究核心中心旨在支持和促进以下两个领域的研究、促进合作并设定新的研究方向：1）工程，2）成像/形态学。 核心 B：工程 - 工程核心将开发和维护快速变化的技术方面的专业知识，以支持科学应用的新型创新支持技术：数字信号处理 (DSP)、通信接口和控制器。 该核心还将与特定项目的工程师互动，提供这些领域的核心硬件和软件组件，以便集成到研究项目中。 核心 C：成像和形态学 - 旨在为 HEI 科学家提供最先进的活体成像、形态学和显微镜服务以及培训。 此类服务包括所有成像设备的检查和维护、图像存储和分析、形态测量和培训。 组织学技术人员的加入将有助于实现这一目标。 增加一名全职共焦技术人员尤为重要，因为我们正在购买两台功能增强的新型激光扫描共焦显微镜，以取代我们 10 年前最初购买的显微镜。 该核心将对所有成像和组织处理设备进行检查和维护。 该核心还将鼓励有关成像领域进展的合作和信息传播。 核心B 工程核心 导演：罗伯特·香农博士 描述（由申请人提供）：HEI Engineering 核心提供高度技术性的工程专业知识，为各种科学家面临的实际问题提供尖端的技术解决方案。 工程解决方案本质上是间歇性的，需要几个月的高技能工程专业知识，但这种情况很少见。 个别研究者通常没有足够的持续工程需求来证明全职工程人员的合理性。工程核心将保持快速变化技术方面的专业知识，以支持科学应用的新型创新技术。 涉及听觉假体和听力评估系统的现代听觉研究在很大程度上依赖于数字信息的实时处理。 工程核心将保持实时数字信号处理 (DSP) 硬件和软件方面的专业知识（目标 1）。 工程核心将开发和维护 USB 和 IEEE 1394 等通信接口的专业知识，以及实验室仪器的主机和专用硬件/软件平台（目标 2）。 许多实验应用需要精确触发和协调多台设备，时间尺度短至微秒，图像数据的空间分辨率在微米范围内。 工程核心将开发和维护硬件和软件，以实现对各种设备的精确控制（目标 3）。