Core--Animal surgery and TBI /SCI model

核心--动物外科与TBI/SCI模型

• 批准号: 7060631
• 负责人: STEPHEN W SCHEFF
• 金额: $ 16.9万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7060631
• 关键词: analgesia; biomedical facility; brain injury; disease /disorder model; laboratory mouse; laboratory rat; postoperative state; spinal cord injury; trauma; veterinary science

The Animal Surgery & TBI/SCI Model Core will be available to all members of the center and their students and technicians. Services provided by this core will include: assistance in performing 1) traumatic brain injury using one of the standard closed head injury models (controlled cortical impact, fluid percussion, Marmarou diffuse impact-acceleration); 2) spinal cord injury (NYU device, IH 0400 device OSU device). The facility will be designed to handle both rats and mice with the stipulation that only one species will be present at any given surgery appointment. The core facility will also provided assistance in post-injury animal welfare and care including bladder expression following SCI.

动物手术和 TBI/SCI 模型核心将向中心的所有成员及其成员开放 学生和技术人员。该核心提供的服务将包括： 协助执行 1) 使用标准闭合性头部损伤模型之一（受控皮质冲击、液体冲击、Marmarou 弥散冲击加速）进行创伤性脑损伤； 2)脊髓损伤(NYU装置、IH 0400装置OSU装置)。该设施将设计用于处理大鼠和小鼠，但规定在任何特定的手术预约中只能有一种物种在场。核心设施还将提供受伤后动物福利和护理方面的援助，包括 SCI 后的膀胱表达。